Socs6 - suppressor of cytokine signaling 6 Gene

Also Known as Cis4; SSI4; Cish4; STAI4; Socs4; SOCS-4; SOCS-6; STATI4; HSPC060; 1500012M23Rik; 5830401B18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54607

Summary

Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Acts upstream of or within negative regulation of T cell activation and regulation of growth. Predicted to be located in immunological synapse. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in several structures, including jaw; medulla oblongata basal plate mantle layer; and retina. Orthologous to human SOCS6 (suppressor of cytokine signaling 6). [provided by Alliance of Genome Resources, Apr 2022]

Socs6 Products (1)

mRNA Protein Name
NM_018821.5 NP_061291.2 suppressor of cytokine signaling 6

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12052866 MGI
Biological Process GO Annotation Evidence References Source
NOT acts upstream of or within intracellular glucose homeostasis IMP
IMP: Inferred from mutant phenotype
12052866 MGI
acts upstream of or within negative regulation of T cell activation IDA
IDA: Inferred from direct assay
20007709 MGI
acts upstream of or within regulation of growth IMP
IMP: Inferred from mutant phenotype
12052866 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

suppressor of cytokine signaling 6

  • CIS-4

  • SH2 domain containing SOCS box protein SOCS6

  • cytokine inducible SH2-containing protein 4

  • cytokine inducible SH2-containing protein CIS4

  • cytokine-inducible SH2 protein 4

  • suppressor of cytokine signaling 4

Socs6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Socs6 Q9JLY0 RBCK1 Homo sapiens Q9BYM8
Y2H Array
16643902
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-156395 MN551 Inducer 98.01% Unkown
HY-RS13557 SOCS6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Socs6 NCBI NCBI:9306