PPARG - peroxisome proliferator activated receptor gamma Gene

Also Known as GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 5468

About PPARG

Cytogenetic location: 3p25.2 Genomic coordinates (GRCh38): 3:12,287,368-12,434,344 (from NCBI)

This gene has 34 transcripts (splice variants), 405 orthologues, 18 paralogues and is associated with 95 phenotypes. Biased expression in fat (RPKM 44.7), urinary bladder (RPKM 10.3) and 11 other tissues.

Summary

This gene encodes a member of the Peroxisome Proliferator-activated Receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and Cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

PPARG Products (16)

mRNA	Protein	Name
NM_001354670.2	NP_001341599.1	peroxisome proliferator-activated receptor gamma isoform 6
NM_001354668.2	NP_001341597.1	peroxisome proliferator-activated receptor gamma isoform 4
NM_001374262.3	NP_001361191.2	peroxisome proliferator-activated receptor gamma isoform 3
NM_138712.5	NP_619726.3	peroxisome proliferator-activated receptor gamma isoform 1
NM_001374261.3	NP_001361190.2	peroxisome proliferator-activated receptor gamma isoform 3
NM_138711.6	NP_619725.3	peroxisome proliferator-activated receptor gamma isoform 1
NM_001374263.2	NP_001361192.2	peroxisome proliferator-activated receptor gamma isoform 1
NM_001354667.3	NP_001341596.2	peroxisome proliferator-activated receptor gamma isoform 1
NM_001354669.2	NP_001341598.1	peroxisome proliferator-activated receptor gamma isoform 5
NM_015869.5	NP_056953.2	peroxisome proliferator-activated receptor gamma isoform 2
NM_001354666.3	NP_001341595.2	peroxisome proliferator-activated receptor gamma isoform 1
NM_001374264.2	NP_001361193.2	peroxisome proliferator-activated receptor gamma isoform 1
NM_001374266.1	NP_001361195.1	peroxisome proliferator-activated receptor gamma isoform 8
NM_005037.7	NP_005028.5	peroxisome proliferator-activated receptor gamma isoform 1
NM_001330615.4	NP_001317544.2	peroxisome proliferator-activated receptor gamma isoform 3
NM_001374265.1	NP_001361194.1	peroxisome proliferator-activated receptor gamma isoform 7

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables DNA binding	IDA IDA: Inferred from direct assay	18382765	GOA
enables DNA binding domain binding	IDA IDA: Inferred from direct assay	19043829	GOA
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	25704091	GOA
enables DNA-binding transcription factor activity	IDA IDA: Inferred from direct assay	9568715	GOA
enables DNA-binding transcription factor binding	IDA IDA: Inferred from direct assay	10622252	GOA
enables LBD domain binding	IDA IDA: Inferred from direct assay	19043829	GOA
enables R-SMAD binding	IPI IPI: Inferred from physical interaction	31023188	GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	25704091	GOA
enables STAT family protein binding	IPI IPI: Inferred from physical interaction	28467929	GOA
enables WW domain binding	IMP IMP: Inferred from mutant phenotype	22292086	GOA
enables alpha-actinin binding	IPI IPI: Inferred from physical interaction	22351778	GOA
enables double-stranded DNA binding	IMP IMP: Inferred from mutant phenotype	19043829	GOA
enables enzyme binding	IPI IPI: Inferred from physical interaction	12039952	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	17937915	GOA
enables nuclear receptor activity	IDA IDA: Inferred from direct assay	10622252	GOA
enables nuclear retinoid X receptor binding	IDA IDA: Inferred from direct assay	9568715	GOA
enables nuclear retinoid X receptor binding	IPI IPI: Inferred from physical interaction	19043829	GOA
enables nucleic acid binding	EXP EXP: Inferred from Experiment	19043829	GOA
enables peptide binding	IDA IDA: Inferred from direct assay	19043829	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	12040021	GOA
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	9568716	GOA
enables transcription cis-regulatory region binding	IDA IDA: Inferred from direct assay	18293083	GOA
enables transcription coregulator binding	IPI IPI: Inferred from physical interaction	14701856	GOA
enables zinc ion binding	IDA IDA: Inferred from direct assay	19043829	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in BMP signaling pathway	IGI IGI: Inferred from genetic interaction	18382765	GOA
involved in cell maturation	IDA IDA: Inferred from direct assay	9568716	GOA
involved in cellular response to insulin stimulus	IMP IMP: Inferred from mutant phenotype	10622252	GOA
involved in cellular response to low-density lipoprotein particle stimulus	IDA IDA: Inferred from direct assay	9568716	GOA
involved in glucose homeostasis	IMP IMP: Inferred from mutant phenotype	10622252	GOA
involved in lipoprotein transport	IDA IDA: Inferred from direct assay	9568716	GOA
involved in mRNA transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	16373399	GOA
involved in monocyte differentiation	IDA IDA: Inferred from direct assay	9568716	GOA
acts upstream of or within negative regulation of BMP signaling pathway	IMP IMP: Inferred from mutant phenotype	21743293	GOA
involved in negative regulation of MAPK cascade	IDA IDA: Inferred from direct assay	18382765	GOA
involved in negative regulation of SMAD protein signal transduction	IGI IGI: Inferred from genetic interaction	28467929	GOA
involved in negative regulation of angiogenesis	IDA IDA: Inferred from direct assay	28566713	GOA
involved in negative regulation of blood vessel endothelial cell migration	IDA IDA: Inferred from direct assay	28566713	GOA
involved in negative regulation of cellular response to transforming growth factor beta stimulus	IGI IGI: Inferred from genetic interaction	28467929	GOA
involved in negative regulation of cholesterol storage	IDA IDA: Inferred from direct assay	19114110	GOA
involved in negative regulation of extracellular matrix assembly	IDA IDA: Inferred from direct assay	25704091	GOA
involved in negative regulation of gene expression	IDA IDA: Inferred from direct assay	28467929	GOA
involved in negative regulation of gene expression	IGI IGI: Inferred from genetic interaction	28467929	GOA
involved in negative regulation of macrophage derived foam cell differentiation	IDA IDA: Inferred from direct assay	19114110	GOA
acts upstream of or within negative regulation of miRNA transcription	IDA IDA: Inferred from direct assay	24751522	GOA
involved in negative regulation of miRNA transcription	IMP IMP: Inferred from mutant phenotype	28522568	GOA
involved in negative regulation of mitochondrial fission	IMP IMP: Inferred from mutant phenotype	29182484	GOA
acts upstream of negative regulation of osteoblast differentiation	IMP IMP: Inferred from mutant phenotype	21042576	GOA
acts upstream of negative regulation of receptor signaling pathway via STAT	IDA IDA: Inferred from direct assay	28467929	GOA
involved in negative regulation of sequestering of triglyceride	IDA IDA: Inferred from direct assay	12700342	GOA
acts upstream of negative regulation of signaling receptor activity	IDA IDA: Inferred from direct assay	12700342	GOA
acts upstream of negative regulation of smooth muscle cell proliferation	IDA IDA: Inferred from direct assay	18382765	GOA
acts upstream of negative regulation of smooth muscle cell proliferation	IGI IGI: Inferred from genetic interaction	28467929	GOA
acts upstream of negative regulation of smooth muscle cell proliferation	IMP IMP: Inferred from mutant phenotype	29182484	GOA
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	12700342	GOA
involved in negative regulation of transforming growth factor beta receptor signaling pathway	IDA IDA: Inferred from direct assay	31023188	GOA
acts upstream of or within negative regulation of transforming growth factor beta receptor signaling pathway	IGI IGI: Inferred from genetic interaction	28467929	GOA
involved in negative regulation of type II interferon-mediated signaling pathway	IMP IMP: Inferred from mutant phenotype	21268089	GOA
involved in negative regulation of vascular associated smooth muscle cell proliferation	IDA IDA: Inferred from direct assay	28522568	GOA
involved in negative regulation of vascular associated smooth muscle cell proliferation	IMP IMP: Inferred from mutant phenotype	24960162	GOA
involved in negative regulation of vascular endothelial cell proliferation	IMP IMP: Inferred from mutant phenotype	24244514	GOA
involved in peroxisome proliferator activated receptor signaling pathway	IDA IDA: Inferred from direct assay	25704091	GOA
involved in peroxisome proliferator activated receptor signaling pathway	IGI IGI: Inferred from genetic interaction	28467929	GOA
involved in peroxisome proliferator activated receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	20622039	GOA
involved in positive regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	19043829	GOA
involved in positive regulation of apoptotic signaling pathway	IDA IDA: Inferred from direct assay	18293083	GOA
acts upstream of positive regulation of cholesterol efflux	IDA IDA: Inferred from direct assay	24751522	GOA
acts upstream of positive regulation of cholesterol transport	IDA IDA: Inferred from direct assay	17611579	GOA
acts upstream of or within positive regulation of gene expression	IDA IDA: Inferred from direct assay	18382765	GOA
involved in positive regulation of gene expression	IGI IGI: Inferred from genetic interaction	28467929	GOA
involved in positive regulation of gene expression	IMP IMP: Inferred from mutant phenotype	29182484	GOA
acts upstream of positive regulation of low-density lipoprotein receptor activity	IDA IDA: Inferred from direct assay	9568716	GOA
involved in positive regulation of miRNA transcription	IDA IDA: Inferred from direct assay	25704091	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	9568715	GOA
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	20622039	GOA
involved in positive regulation of vascular associated smooth muscle cell apoptotic process	IMP IMP: Inferred from mutant phenotype	28522568	GOA
involved in regulation of blood pressure	IMP IMP: Inferred from mutant phenotype	10622252	GOA
involved in retinoic acid receptor signaling pathway	IDA IDA: Inferred from direct assay	16239304	GOA
involved in signal transduction	IDA IDA: Inferred from direct assay	9568716	GOA

Cellular Component GO Annotation	Evidence	References	Source
part of RNA polymerase II transcription regulator complex	EXP EXP: Inferred from Experiment	15258145	GOA
part of RNA polymerase II transcription regulator complex	IDA IDA: Inferred from direct assay	9568716	GOA
is active in nucleus	IDA IDA: Inferred from direct assay	18382765	GOA
located in nucleus	IDA IDA: Inferred from direct assay	9568716	GOA
part of receptor complex	IDA IDA: Inferred from direct assay	19043829	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PPARG Protein Structure

PPARgamma_N

zf-C4

Hormone_recep

0
100
200
300
400
505 a.a.

Protein Preferred Names	Protein Names
peroxisome proliferator-activated receptor gamma	PPAR-gamma nuclear receptor subfamily 1 group C member 3 peroxisome proliferator-activated receptor-gamma 5 peroxisome proliferator-activated receptor-gamma splicing

PPARG Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	PPARG	P37231	GATA5	Homo sapiens	Q9BWX5	Validated Y2H	32296183
Intra	PPARG	P37231	SIRT1	Homo sapiens	Q96EB6	CH-IP	20660480
Intra	PPARG	P37231	ADCY4	Homo sapiens	Q8NFM4	Validated Y2H	32296183
Intra	PPARG	P37231	NCOR1	Homo sapiens	O75376	Alpha-Screen	21775429
Intra	PPARG	P37231	NCOR1	Homo sapiens	O75376	BioID	35140242
Intra	PPARG	P37231	HTT	Homo sapiens	P42858	Y2H Array	32814053
Intra	PPARG	P37231	HTT	Homo sapiens	P42858	Y2H Pooling	32814053
Intra	PPARG	P37231	HTT	Homo sapiens	P42858	Y2H	17500595
Intra	PPARG	P37231	HTT	Homo sapiens	P42858	Validated Y2H	32814053
Intra	PPARG	P37231	SMARCD3	Homo sapiens	Q6STE5-1	Pull Down	14701856
Intra	PPARG	P37231	SMARCD3	Homo sapiens	Q6STE5-2	Pull Down	14701856
Intra	PPARG	P37231	MAPK9	Homo sapiens	P45984	Validated Y2H	32296183
Intra	PPARG	P37231	RXRB	Homo sapiens	P28702	Y2H Array	20211142
Intra	PPARG	P37231	RXRB	Homo sapiens	P28702	TAP	25609649
Intra	PPARG	P37231	PPARGC1A	Homo sapiens	Q9UBK2	Y2H	12522104
Intra	PPARG	P37231	RXRA	Homo sapiens	P19793	TAP	25609649
Intra	PPARG	P37231	RXRA	Homo sapiens	P19793	Y2H Array	20211142
Intra	PPARG	P37231	RXRA	Homo sapiens	P19793	BioID	35140242

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant PPARG Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7999	PPAR gamma Protein, Human (His)	P37231-1 (D238-D503)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P73701	PPAR gamma Protein, Human (sf9, His-GST)	P37231-1 (M1-Y505)	≥ 80%, as determined by reducing SDS-PAGE.
HY-P700275	PPAR gamma Protein, Human (C-His, solution)	P37231-1 (D238-D503)	≥ 90%, as determined by reducing SDS-PAGE.

PPARG Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80436	PPAR gamma Antibody (YA122)	WB	Human, Rat
HY-P80872	PPAR gamma Antibody	ICC/IF, WB, IHC-F, IHC-P, ELISA	Human, Mouse, Rat
HY-P85457	PPAR gamma Antibody (YA5149)	WB, ICC/IF	Human, Mouse, Rat, Bovine, Dog, Goat, Pig, Rabbit, Sheep
HY-P85702	PPAR gamma Antibody (YA5394)	WB, IHC-P, IP	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Glioblastoma	Glioblastoma Multiforme Gbm Adult Glioblastoma Multiforme Grade Iv Adult Astrocytic Tumor Primary Glioblastoma Multiforme Spongioblastoma Multiforme Adult Glioblastoma Primary Glioblastoma
Hyperglycemia
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Protection Against Lung Cancer, Susceptibility To Adenocarcinoma Of Lung, Somatic Nonsmall Cell Lung Cancer Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1
Arrhythmogenic Right Ventricular Cardiomyopathy	Arrhythmogenic Right Ventricular Dysplasia Arvc Arvd Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Arvc Cardiomyopathy Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia Arvd/C Right Ventricular Dysplasia, Arrhythmogenic Ventricular Dysplasia, Right, Arrhythmogenic Cardiomyopathy, Ventricular, Right, Arrhythmogenic Dysplasia, Arrhythmogenic Right Ventricular
Skin Disease	Skin Diseases Abnormality Of The Skin Skin Diseases, Genetic Genodermatosis Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Carbohydrate Metabolic Disorder	Inborn Errors Of Carbohydrate Metabolism Disorder Of Carbohydrate Metabolism Carbohydrate Metabolism, Inborn Errors Disorder Of Carbohydrate Transport And Metabolism Inborn Carbohydrate Metabolism Disorder Inborn Carbohydrate Metabolic Disorder Carbohydrate Metabolism Disorder Carbohydrate Metabolism Disorders Disorders Of Carbohydrate Metabolism Congenital Disorders Of Carbohydrate Metabolism Inherited Disorders Of Carbohydrate Metabolism
Thyroid Gland Anaplastic Carcinoma	Anaplastic Thyroid Carcinoma Anaplastic Thyroid Cancer Thyroid Cancer, Anaplastic Thyroid Carcinoma, Anaplastic Thyroid Carcinoma Anaplastic
Carotid Intimal Medial Thickness 1	Cimt1 Intimal Medial Thickness Of Internal Carotid Artery
B-Cell Lymphoma	Lymphoma, B-Cell B-Cell Lymphomas B-Cell Lymphocytic Neoplasm Lymphoma B-Cell B-Cell Lymphoma Nos
Lipodystrophy, Congenital Generalized, Type 2	Congenital Generalized Lipodystrophy Type 2 CGL2 Berardinelli-Seip Congenital Lipodystrophy Type 2 Berardinelli-Seip Syndrome Brunzell Syndrome Bscl2-Related Total Lipodystrophy And Acromegaloid Gigantism Berardinelli-Seip Congenital Lipodystrophy, Type 2 Seip Syndrome Berardinelli Syndrome Lipodystrophy, Total, And Acromegaloid Gigantism Lipoatrophic Diabetes, Congenital Lipodystrophy, Berardinelli-Seip Congenital, Type 2 Brunzell Syndrome, Bscl2-Related Congenital Lipoatrophic Diabetes Congenital Generalized Lipodystrophy 2 Lipoatrophic Diabetes Lipodystrophy Berardinelli Type Familial Generalized Lipodystrophy Lipoatrophic Diabetes Mellitus Familial Partial Lipodystrophy, Type 2
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Cryptogenic Fibrosing Alveolitis Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Ovarian Disease	Ovarian Dysfunction Ovarian Diseases Ovarian Disorders Disorder Of Endocrine Ovary
Lipedema
Amyotrophic Lateral Sclerosis 1	Amyotrophic Lateral Sclerosis ALS Lou Gehrig Disease Amyotrophic Lateral Sclerosis Type 1 Charcot Disease ALS1 Amyotrophic Lateral Sclerosis, Susceptibility To Fals Lou Gehrig'S Disease Mnd Motor Neuron Disease Familial Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis 1, Familial Amyotrophic Lateral Sclerosis 1, Autosomal Dominant Motor Neuron Disease, Bulbar Motor Neurone Disease Amyotrophic Lateral Sclerosis With Dementia Dementia With Amyotrophic Lateral Sclerosis Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic Sclerosis, Lateral, Amyotrophic, Type 1 Amyotrophic Sclerosis Als - [Amyotrophic Lateral Sclerosis] Wasting Palsy Amyotrophic Paralysis Amyotrophy Lateral Sclerosis Wasting Paralysis Spinal Progressive Amyotrophy Progressive Atrophic Paralysis
Middle East Respiratory Syndrome	Mers Mers - [Middle East Respiratory Syndrome]
Abdominal Obesity-Metabolic Syndrome Quantitative Trait Locus 2	Abdominal Obesity-Metabolic Syndrome Abdominal Obesity Metabolic Syndrome Metabolic Syndrome X Aoms2 Aoms1
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
Leptin Deficiency Or Dysfunction	Morbid Obesity Obesity Due To Congenital Leptin Deficiency LEPD Congenital Leptin Deficiency Obesity, Morbid Obesity, Morbid, Due To Leptin Deficiency Severe Obesity Obesity, Morbid, Nonsyndromic 1 Leptin Deficiency Obesity, Severe, Due To Leptin Deficiency Morbid Obesity Due To Leptin Deficiency Obesity Morbid Leptin Dysfunction Leptin
Ulcer Of Lower Limbs	Ulcer Of Ankle Ulcer Of Calf Ulcer Of Heel And Midfoot Ulcer Of Thigh Ulcer Of Lower Limb
Colonic Benign Neoplasm	Colon Neoplasm Colonic Mass Colonic Tumor Neoplasm Of Colon Neoplasm Of The Colon Colonic Neoplasms Colon Cancer Colon Carcinoma Nos Colonic Cancer Metastatic Colon Cancer Nos
Thyroid Gland Disease	Abnormality Of The Thyroid Gland Thyroid Diseases
Polycystic Ovary Syndrome	Polycystic Ovarian Syndrome Pcos Polycystic Ovaries Stein-Leventhal Syndrome Multicystic Ovaries Polycystic Ovarian Disease Polycystic Ovary Sclerocystic Ovaries Sclerocystic Ovary Syndrome Stein-Leventhal Synd. Cystic Disease Of Ovaries Cystic Disease Of Ovary Pco Pcod Sclerocystic Ovarian Degeneration Polycystic Ovary Syndrome, Susceptibility To Pcos - [Polycystic Ovary Syndrome] Polycystic Ovary Nos Pco - [Polycystic Ovary]
Hypertrophic Cardiomyopathy	Hypertrophic Obstructive Cardiomyopathy Cardiomyopathy, Hypertrophic Cardiomyopathy, Hypertrophic, Familial Familial Hypertrophic Cardiomyopathy Cardiomyopathy Hypertrophic Obstructive Idiopathic Myocardial Hypertrophy Idiopathic Hypertrophic Cardiomyopathy Obstructive Idiopathic Hypertrophic Cardiomyopathy Obstructive Cardiomyopathy Idiopathic Hypertrophic Subaortic Stenosis Muscular Subaortic Stenosis Hypertrophic Obstructive Subaortic Stenosis
Fatty Liver Disease	Alcoholic Fatty Liver Fatty Liver Fatty Liver, Alcoholic Fatty Change Of Liver Hepatic Lipidosis Steatosis Of Liver Fatty Liver Alcoholic Steatohepatitis Etoh Fatty Liver Etoh Fatty Liver Metamorphosis Fatty Etoh Liver Necrosis
Pulmonary Fibrosis	Fibrosis Of Lung
Familial Partial Lipodystrophy	Lipodystrophy, Familial Partial Fpld Kobberling-Dunnigan Syndrome Dunnigan Syndrome Koberling-Dunnigan Syndrome Dunnigan-Kobberling Syndrome Fpl Familial Partial Lipodystrophy, Type 2
Lipid Metabolism Disorder	Dyslipidemia Disorder Of Fatty Acid Metabolism Lipid Metabolism Disorders Fatty Acid Metabolism Disorder Disorder Of Lipid Metabolism Abnormality Of Lipid Metabolism Lipid Metabolism, Inborn Errors Dyslipidemias Disorders Of Lipid Metabolism Congenital Disorders Of Lipid Metabolism Inherited Disorders Of Lipid Metabolism
Complete Generalized Lipodystrophy
Frontal Fibrosing Alopecia	Lichen Planopilaris Lichen Planus Follicularis Follicular Lichen Planus Ffa Lpp Lichen Follicularis Kossard Disease Lichen Planopilaris Classic Type Postmenopausal Frontal Fibrosing Alopecia
Overnutrition
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Congenital Anomaly Of Heart Heart Defect Heart Malformation Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Gliosarcoma	Glioblastoma With Sarcomatous Component Sarcomatous Glioblastoma
Aging
Myocardial Infarction	Heart Attack Myocardial Infarction, Susceptibility To Myocardial Infarction 1 Myocardial Infarction, Protection Against Myocardial Infarction, Decreased Susceptibility To Myocardial Infarction, Decreased Myocardial Infarct MCI1 Premature Myocardial Infarction Myocardial Infarction, Susceptibility To, Type 1
Proteasome-Associated Autoinflammatory Syndrome 1	Jmp Syndrome Nakajo-Nishimura Syndrome Nkjo Autoinflammation, Lipodystrophy, And Dermatosis Syndrome Proteasome-Associated Autoinflammatory Syndrome 1 And Digenic Forms Nakajo Syndrome PRAAS1 Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy And Elevated Temperature Syndrome Candle Joint Contractures, Muscular Atrophy, Microcytic Anemia, And Panniculitis-Induced Lipodystrophy Aldd Joint Contractures - Muscle Atrophy - Microcytic Anemia - Panniculitis-Induced Lipodystrophy Nakajo Nishimura Syndrome Amyotrophy Fat Tissue Anomaly Japanese Autoinflammatory Syndrome With Lipodystrophy Jasl Joint Contractures Muscular Atrophy Microcytic Anemia And Panniculitis-Induced Lipodystrophy Nns Nodular Erythema With Digital Changes Secondary Hypertrophic Osteoperiostosis With Pernio Inflammation
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Schizophrenia	SCZD Schizophrenia With Or Without An Affective Disorder Schizophrenia 12 Schizophrenia, Susceptibility To Schizophrenia-1 Dementia Praecox Schizophrenia 1
Glucose Intolerance	Glucose: Intolerance Glucose: Malabsorption Malabsorption Of Glucose Impaired Glucose Tolerance
Salivary Gland Carcinoma	Salivary Gland Cancer Malignant Neoplasm Of Salivary Gland Salivary Gland Neoplasms
Hyperinsulinism	Hyperinsulinemia
Arteriosclerosis	Arteriosclerotic Vascular Disease
Lipid Storage Disease	Lipoidosis Inborn Lipid Storage Disorder Lipoid Storage Diseas Lipid Storage Diseases Lipidoses
Microphthalmia, Isolated 1	Isolated Microphthalmia 1 MCOP1 Mcop Anophthalmia, Clinical, Isolated Microphthalmos, Autosomal Recessive
Acquired Metabolic Disease
Huntington Disease	Huntington'S Disease Huntington Chorea HD Huntington'S Chorea Huntington Chronic Progressive Hereditary Chorea Juvenile Huntington Disease Chronic Progressive Chorea Chronic Progressive Hereditary Chorea Hc - [Huntington Chorea] Hereditary Chorea Progressive Hereditary Chorea
Follicular Adenoma	Follicular Adenoma Of The Thyroid Gland Thyroid Follicular Adenoma Adenoma Follicular Follicular Thyroid Adenoma Thyroid Gland Follicular Adenoma
Hyperuricemia	Blood Urate Raized Uricacidemia
Nelson Syndrome	Nelson'S Syndrome Dermal Ridges Ridges-Off-The-End Syndrome Postadrenalectomy Cushing Syndrome
Amelogenesis Imperfecta, Type Ig	Enamel-Renal Syndrome Ers Amelogenesis Imperfecta Type 1g AI1G Enamel-Renal-Gingival Syndrome Amelogenesis Imperfecta And Gingival Fibromatosis Syndrome Aigfs Amelogenesis Imperfecta, Hypoplastic, With Nephrocalcinosis Amelogenesis Imperfecta Hypoplastic With Nephrocalcinosis Amelogenesis Imperfecta Type Ig Amelogenesis Imperfecta-Nephrocalcinosis Syndrome Amelogenesis Imperfecta 1g Hypoplastic Amelogenesis Imperfecta With Nephrocalcinosis Amelogenesis Imperfecta Nephrocalcinosis
Tangier Disease	Analphalipoproteinemia High Density Lipoprotein Deficiency, Tangier Type TGD High Density Lipoprotein Deficiency, Type 1 Hdldt1 Familial High Density Lipoprotein Deficiency A-Alphalipoprotein Neuropathy Alpha High Density Lipoprotein Deficiency Disease Cholesterol Thesaurismosis Familial High Density Lipoprotein Deficiency Disease Hdl Lipoprotein Deficiency Disease Tangier Disease Neuropathy Familial Alpha-Lipoprotein Deficiency Familial High-Density Lipoprotein Deficiency 1 Primary Hypoalphalipoproteinemia 1 Analphalipo-Proteinemia Familial Hypoalphalipo-Proteinemia Familial Hypoalphalipoproteinemia Lipoprotein Deficiency Disease, Hdl, Familial Tangier Hereditary Neuropathy Atp-Binding Cassette Transporter A1 Deficiency Hdld1 High Density Lipoprotein Deficiency 1 Tangier Disease, Variant Hypoalphalipoproteinemia, Familial Familial Hdl Deficiency
Sebaceous Gland Disease	Sebaceous Gland Anomaly Sebaceous Gland Diseases
Cardiovascular System Disease	Abnormality Of The Cardiovascular System Disease Of Subdivision Of Hemolymphoid System Disorder Of Cardiovascular System Cardiovascular Diseases Cardiovascular Disease
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Obesity , Susceptibility To Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Differentiated Thyroid Carcinoma	Papillary Or Follicular Thyroid Carcinoma Well-Differentiated Thyroid Carcinoma Differentiated Thyroid Gland Carcinoma
Amelogenesis Imperfecta	Ai Congenital Enamel Hypoplasia Al - [Amelogenesis Imperfecta]
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Disease, Susceptibility To Coronary Artery Anomaly Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
Lysosomal Storage Disease	Lysosomal Storage Diseases Disorder Of Lysosomal Enzyme Inborn Lysosomal Enzyme Disorder Lysosomal Storage Metabolism Disorder Lysosomal Storage Disorder
Thyroid Gland Cancer	Thyroid Gland Carcinoma Malignant Neoplasm Of Thyroid Gland Malignant Tumour Of Thyroid Gland Thyroid Neoplasm Thyroid Neoplasms Neoplasm Of Thyroid Gland Thyroid Gland Neoplasm Head And Neck Cancer, Thyroid Neoplasm Of The Thyroid Gland Cancer Of The Thyroid Primary Malignant Neoplasm Of Thyroglossal Duct Malignant Neoplasm Of Thyroglossal Duct Primary Malignant Neoplasm Of Thyroid Gland Thyroglossal Duct Cancer Toxic Goitre Malignant Tumour Cancerous Goitre
Giant Cell Glioblastoma	Monstrocellular Sarcoma
Acquired Generalized Lipodystrophy	Lawrence Syndrome Acquired Lipoatrophic Diabetes Lawrence-Seip Syndrome Familial Generalized Lipodystrophy
Retinoblastoma	RB Trilateral Retinoblastoma RB1 Retinoblastoma, Trilateral Neuroblastoma Of Retina Rb - Retinoblastoma Eye Cancer, Retinoblastoma Retinal Cancer Retinal Tumor Glioma, Retinal Non-Hereditary Retinoblastoma Childhood Cancer Retinoblastoma Malignant Neoplasm Of Retina Retinal Neoplasms
Laryngeal Cartilage Cancer	Malignant Neoplasm Of Laryngeal Cartilage Malignant Neoplasm Of Laryngeal Cartilages Malignant Tumor Of Laryngeal Cartilage Primary Malignant Neoplasm Of Laryngeal Cartilage
Multiple Sclerosis	MS Multiple Sclerosis, Susceptibility To Disseminated Sclerosis Multiple Sclerosis, Disease Progression, Modifier Of Insular Sclerosis Multiple Sclerosis Modifier Of Disease Progression Multiple Sclerosis, Susceptibility To 1 Multiple Sclerosis, Susceptibility To, 1 Multiple Sclerosis 1 Generalized Multiple Sclerosis Multiple Sclerosis Variant Multiple Sclerosis Susceptibility To Cerebrospinal Sclerosis Generalised Multiple Sclerosis Ms - [Multiple Sclerosis] Disseminated Cerebrospinal Sclerosis Disseminated Multiple Sclerosis Disseminated Nervous System Myelosclerosis Multiple Cerebrospinal Sclerosis Multiple Combined Sclerosis Multiple Sclerosis Generalised Disseminated Brain Sclerosis Disseminated Spinal Sclerosis Insular Brain Sclerosis Miliary Brain Sclerosis Multiple Combined Sclerosis Of Spinal Cord Multiple Ascending Sclerosis Multiple Brain Sclerosis Multiple Sclerosis Of Brain Stem Multiple Sclerosis Of The Brain Stem Multiple Sclerosis Of Cord Sclérose En Plaques Plaque Sclerosis Multiple Sclerosis Of The Spinal Cord
Hyperandrogenism	Hyperandrogenization Syndrome
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Adult Syndrome	Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome Acro Dermato Ungual Lacrimal Tooth Syndrome Pigment Anomaly-Ectrodactyly-Hypodontia Syndrome Acro-Dermato-Ungual-Lacrimal-Tooth Syndrome Adult
Lipodystrophy, Familial Partial, Type 2	FPLD2 Lipoatrophic Diabetes Familial Partial Lipodystrophy Type 2 Familial Partial Lipodystrophy, Dunnigan Type Fpl2 Lipoatrophic Diabetes Mellitus Lipodystrophy, Familial Partial, Dunnigan Type Lipodystrophy, Familial, Of Limbs And Lower Trunk Lipodystrophy, Reverse Partial Familial Partial Lipodystrophy Dunnigan Type Dunnigan Syndrome Familial Lipodystrophy Of Limbs And Lower Trunk Reverse Partial Lipodystrophy Lipodystrophy, Familial Partial, 2 Generalized Lipoatrophy Associated With Diabetes, Hepatic Steatosis, Hypertrophic Cardiomyopathy And Leukomelanodermic Papules Lipodystrophy Familial Of Limbs And Lower Trunk Lipodystrophy Reverse Partial Diabetes Mellitus, Lipoatrophic Familial Partial Lipodystrophy, Type 2 Familial Generalized Lipodystrophy
Neuroblastoma	Nb Neuroblastoma, Susceptibility To Neuroblastomas Central Neuroblastoma
Lipodystrophy, Familial Partial, Type 3	FPLD3 Pparg-Related Familial Partial Lipodystrophy Familial Partial Lipodystrophy Type 3 Familial Partial Lipodystrophy Associated With Pparg Mutations Pparg-Related Fpld Lipodystrophy, Familial Partial, Associated With Pparg Mutations Insulin Resistance, Severe, Digenic Lipodystrophy, Familial Partial, 3 Familial Partial Lipodystrophy, Type 3
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Glucose Metabolism Disease	Glucose Metabolism Disorders Disorder Of Glucose Metabolism
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Colitis
Liver Disease	Liver Failure Liver Diseases Abnormality Of The Liver Liver Dysfunction Disorder Of Liver Hepatic Disorder Hepatic Disease Disease Of Bilirubin Metabolism Disorder Of Bilirubin Metabolism Liver Decompensation Liver Function Failure Hepatic Failure Nos Liver Failure Nos End Stage Liver Disease Decompensated Liver Failure Decompensation Of Liver Function Hepatic Decompensation Hepatic Insufficiency Liver Cell Necrosis With Hepatic Failure Liver Insufficiency Decompensated Liver Disease End Stage Liver Failure Liver Necrosis With Hepatic Failure
Diabetes Mellitus	Diabetes
Congenital Generalized Lipodystrophy	Berardinelli-Seip Congenital Lipodystrophy Berardinelli-Seip Syndrome Brunzell Syndrome Bscl Generalized Lipodystrophy Lipodystrophy, Congenital Generalized Seip Syndrome Total Lipodystrophy Cgl Lipoatrophic Diabetes Lipodystrophy, Generalized, Congenital Familial Generalized Lipodystrophy Congenital Generalized Lipodystrophy Type 2 Lipoatrophic Diabetes Mellitus Familial Partial Lipodystrophy, Type 2
Thyroid Cancer, Nonmedullary, 2	Thyroid Carcinoma, Follicular Follicular Thyroid Carcinoma NMTC2 Thyroid Cancer, Follicular Thyroid Carcinoma, Follicular, Somatic Ftc Thyroid Cancer, Non-Medullary, 2 Thyroid Follicular Carcinoma Follicular Thyroid Cancer Cancer, Thyroid, Nonmedullary, Type 2 Thyroid Gland Adenocarcinoma Follicular Carcinoma Of Unspecified Site Moderately Differentiated Follicular Carcinoma Of Thyroid Gland Pure Follicle Carcinoma Of Thyroid Gland Pure Follicle Follicular Carcinoma Of Unspecified Site Pure Follicular Carcinoma Of Thyroid Gland Trabecular Follicular Carcinoma Of Thyroid Gland Trabecular Follicular Carcinoma Of Unspecified Site Well Differentiated Follicular Carcinoma Of Unspecified Site Well Differentiated Follicular Carcinoma Of Thyroid Gland
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy
Sleep Apnea	Sleep Apnea Syndromes
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Maturity-Onset Diabetes Of The Young	MODY Maturity Onset Diabetes Mellitus In Young Mason-Type Diabetes Mason Type Diabetes Maturity Onset Diabetes Of The Young Mody Syndrome Diabetes Of The Young, Maturity-Onset
Acne	Acne Vulgaris Acne Varioliformis Frontalis Acne
Platelet Glycoprotein Iv Deficiency	Platelet-Type Bleeding Disorder 10 Bdplt10 Cd36 Deficiency Bleeding Disorder, Platelet-Type, 10 PG4D Bleeding Disorder Platelet-Type 10 Deficiency, Platelet Glycoprotein Iv
Abdominal Obesity-Metabolic Syndrome 1	Metabolic Syndrome X Metabolic Syndrome AOMS1 Dysmetabolic Syndrome X Metabolic Disease Abdominal Obesity Metabolic Syndrome
Liposarcoma	Lipomatous Cancer
Pellagra	Niacin Deficiency Niacin-Tryptophan Deficiency Pellagroid Syndrome
Lipodystrophy, Familial Partial, Type 1	FPLD1 Familial Partial Lipodystrophy Type 1 Familial Partial Lipodystrophy, Kobberling Type Lipodystrophy, Familial Partial, Kobberling Type Familial Partial Lipodystrophy Kobberling Type Familial Partial Lipodystrophy Type Köbberling Familial Partial Lipodystrophy, Köbberling Type Familial Partial Lipodystrophy, Type 1
Marfan Syndrome	MFS Mfs1 Marfan'S Syndrome Marfan Syndrome Type 1 Marfan Syndrome, Type I Mass Phenotype Contractural Arachnodactyly Mass Syndrome Octd Overlap Connective Tissue Disease Marfanoid Hypermobility Syndrome Marfan Disease
Inherited Metabolic Disorder	Inborn Errors Of Metabolism Inborn Metabolism Disorder Metabolic Hereditary Disorder Inborn Error Of Metabolism Inborn Metabolic Disorder Metabolism, Inborn Errors
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Diabetes Mellitus, Non-Insulin-Dependent Type 2 Diabetes T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes
Atherosclerosis Susceptibility	Atherosclerosis Atherosclerosis, Susceptibility To ATHS Atherogenic Lipoprotein Phenotype Alp Arteriosclerosis
Familial Hyperlipidemia	Familial Hyperlipoproteinemia Hyperlipidaemia Hyperlipoproteinemias Hyperlipemia Hyperlipidemias Hyperlipidemia
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Prediabetes Syndrome	Impaired Glucose Tolerance Prediabetes Prediabetic State IGT Igt - [Impaired Glucose Tolerance] Impaired Glucose Tolerance With Unspecified Complication Impaired Glucose Tolerance Without Complication Abnormal Glucose Tolerance
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Vascular Disease	Vascular Diseases Aneurysm Spinal Cord Ischemia Spinal Cord Vascular Diseases Vascular Tissue Disease Vascular Anomaly
Inflammatory Bowel Disease	Inflammatory Bowel Diseases Bowel Disease, Inflammatory
Thyroid Gland Follicular Carcinoma	Follicular Thyroid Carcinoma Follicular Adenocarcinoma Follicular Adenocarcinoma, Well Differentiated Follicular Carcinoma Thyroid Adenocarcinoma Adenocarcinoma, Follicular
Monocytic Leukemia	Monocytic Leukaemia Schilling'S Leukaemia Schilling'S Leukemia M5b Acute Differentiated Monocytic Leukemia
Non-Alcoholic Fatty Liver Disease	Fatty Liver Non-Alcoholic Fatty Liver Nafld Nonalcoholic Fatty Liver Disease Nonalcoholic Steatohepatitis Steatosis Nafl Nash Non-Alcoholic Steatohepatitis Susceptibility To Nonalcoholic Fatty Liver Disease Steatohepatitis Fatty Degeneration Non-Alcoholic Fatty Liver Disease Without Mention Of Non-Alcoholic Steatohepatitis Nafld Without Nash Nafld Without Mention Of Nash
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Non-Alcoholic Steatohepatitis	Nonalcoholic Steatohepatitis Nash Nash - [Non-Alcoholic Steatohepatitis] Non-Alcoholic Steatohepatosis
Pancreatic Cancer	Pancreatic Carcinoma Familial Pancreatic Carcinoma Pancreatic Neoplasm Carcinoma Of Pancreas Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Cancer Of The Pancreas Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Myocarditis	Myocardial Inflammation Inflammatory Cardiomyopathy
Alzheimer Disease 11	Ad11 Alzheimer'S Disease 11 Alzheimer Disease, Familial, 11 Alzheimer Disease-11 Alzheimer'S Disease 11, Late Onset

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-153344	FX-909	Inhibitor	99.79%	Phase 1

Pre-clinical Phase

Bioactive Molecules (12)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-153364	FTX-6746	Inhibitor	99.07%	Unkown
HY-160160	BAY-5516	Inhibitor	98.17%	Unkown
HY-W009066	2-Ethylhexyl diphenyl phosphate		94.27%	Unkown
HY-108569	nTZDpa		98.53%	Unkown
HY-160161	BAY-5094	Inhibitor	98.04%	Unkown
HY-RS10925	PPARG Human Pre-designed siRNA Set A		/	Unkown
HY-RS10926	Pparg Mouse Pre-designed siRNA Set A		/	Unkown
HY-121579	L-764406	Agonist	/	Unkown
HY-160159	PPARγ modulator-1	Modulator	/	Unkown
HY-160188	BAY-9683	Modulator	/	Unkown
HY-178447	PPARγ agonist 20		/	Unkown
HY-RS10927	Pparg Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PPARG	MGD	MGI:97747
Felis catus	PPARG	VGNC	VGNC:68977
Macaca mulatta	PPARG	VGNC	VGNC:76229
Bos taurus	PPARG	VGNC	VGNC:33183
Canis familiaris	PPARG	VGNC	VGNC:44836
Rattus norvegicus	PPARG	RGD	RGD:3371
Others	PPARG	NCBI