PPEF1 - protein phosphatase with EF-hand domain 1 Gene

This gene encodes a member of the serine/threonine protein Phosphatase with EF-hand motif family. The protein contains a protein Phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described. [provided by RefSeq, Jul 2008]