DUSP23 - dual specificity phosphatase 23 Gene

Also Known as VHZ; LDP3; MOSP; LDP-3; DUSP25

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54935

About DUSP23

Cytogenetic location: 1q23.2 Genomic coordinates (GRCh38): 1:159,780,962-159,782,543 (from NCBI)

This gene has 3 transcripts (splice variants) and 181 orthologues. Ubiquitous expression in kidney (RPKM 18.6), liver (RPKM 13.3) and 25 other tissues.

Summary

Enables protein tyrosine/serine/threonine Phosphatase activity. Involved in dephosphorylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DUSP23 Products (3)

mRNA Protein Name
NM_001319658.2 NP_001306587.1 dual specificity protein phosphatase 23
NM_001319659.2 NP_001306588.1 dual specificity protein phosphatase 23
NM_017823.5 NP_060293.2 dual specificity protein phosphatase 23

DUSP23 Protein Structure

DSPc

DSPc: Dual specificity phosphatase, catalytic domain (30 - 145)

  • 0
  • 100
  • 150 a.a.
Protein Preferred Names Protein Names

dual specificity protein phosphatase 23

  • VH1-like member Z

DUSP23 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
DUSP23 Q9BVJ7 BANF2 Homo sapiens Q9H503-2
Y2H Prey Pooling
32296183
Intra
DUSP23 Q9BVJ7 BANF2 Homo sapiens Q9H503-2
Validated Y2H
32296183
Intra
DUSP23 Q9BVJ7 BANF2 Homo sapiens Q9H503-2
Y2H Array
32296183
Intra
DUSP23 Q9BVJ7 TCF4 Homo sapiens P15884-3
Y2H Array
32296183
Intra
DUSP23 Q9BVJ7 TCF4 Homo sapiens P15884-3
Y2H Prey Pooling
32296183
Intra
DUSP23 Q9BVJ7 MRNIP Homo sapiens Q6NTE8
Y2H Array
32296183
Intra
DUSP23 Q9BVJ7 MRNIP Homo sapiens Q6NTE8
Y2H Prey Pooling
32296183
Intra
DUSP23 Q9BVJ7 EXOSC8 Homo sapiens Q96B26
Y2H Array
32296183
Intra
DUSP23 Q9BVJ7 EXOSC8 Homo sapiens Q96B26
Validated Y2H
25910212
Intra
DUSP23 Q9BVJ7 EXOSC8 Homo sapiens Q96B26
Y2H Bait-Prey Pool
25910212
Intra
DUSP23 Q9BVJ7 EXOSC8 Homo sapiens Q96B26
Y2H Array
25910212
Intra
DUSP23 Q9BVJ7 EXOSC8 Homo sapiens Q96B26
Y2H Prey Pooling
32296183
Intra
DUSP23 Q9BVJ7 PSMB8 Homo sapiens P28062-2
Y2H Array
32296183
Intra
DUSP23 Q9BVJ7 PSMB8 Homo sapiens P28062-2
Y2H Prey Pooling
32296183
Intra
DUSP23 Q9BVJ7 ASB6 Homo sapiens Q9NWX5
Y2H Prey Pooling
32296183
Intra
DUSP23 Q9BVJ7 ASB6 Homo sapiens Q9NWX5
Validated Y2H
32296183
Intra
DUSP23 Q9BVJ7 ASB6 Homo sapiens Q9NWX5
Y2H Array
32296183
Intra
DUSP23 Q9BVJ7 UBA3 Homo sapiens Q8TBC4
Y2H Array
32296183
Intra
DUSP23 Q9BVJ7 UBA3 Homo sapiens Q8TBC4
Y2H Prey Pooling
32296183
Intra
DUSP23 Q9BVJ7 NIF3L1 Homo sapiens Q9GZT8
Validated Y2H
25416956
Intra
DUSP23 Q9BVJ7 NIF3L1 Homo sapiens Q9GZT8
Y2H Prey Pooling
25416956
Intra
DUSP23 Q9BVJ7 PSME2 Homo sapiens Q9UL46
Y2H Prey Pooling
32296183
Intra
DUSP23 Q9BVJ7 PSME2 Homo sapiens Q9UL46
Validated Y2H
32296183
Intra
DUSP23 Q9BVJ7 PSME2 Homo sapiens Q9UL46
Y2H Array
32296183
Intra
DUSP23 Q9BVJ7 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
DUSP23 Q9BVJ7 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

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Diseases Alias
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Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04062 DUSP23 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11414 PTPMT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta DUSP23 VGNC VGNC:71880
Mus musculus DUSP23 MGD MGI:1915690
Felis catus DUSP23 VGNC VGNC:107869
Rattus norvegicus DUSP23 RGD RGD:1309202
Bos taurus DUSP23 VGNC VGNC:28257
Others DUSP23 NCBI