2. Gene
  3. SAMD4B - sterile alpha motif domain containing 4B Gene

SAMD4B - sterile alpha motif domain containing 4B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SMGB; Smaug2

Gene ID: 55095 | Gene type: protein coding

About SAMD4B

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:39,342,421-39,390,764 (from NCBI)

This gene has 12 transcripts (splice variants), 200 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 7.6), ovary (RPKM 7.3) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within cerebellar neuron development. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

SAMD4B Products(30)

mRNA Protein Name
NM_001303614.2 NP_001290543.1 protein Smaug homolog 2 isoform b
NM_001384565.1 NP_001371494.1 protein Smaug homolog 2 isoform a
NM_001384566.1 NP_001371495.1 protein Smaug homolog 2 isoform a
NM_001384568.1 NP_001371497.1 protein Smaug homolog 2 isoform a
NM_001384569.1 NP_001371498.1 protein Smaug homolog 2 isoform a
NM_001384570.1 NP_001371499.1 protein Smaug homolog 2 isoform a
NM_001384571.1 NP_001371500.1 protein Smaug homolog 2 isoform a
NM_001384573.1 NP_001371502.1 protein Smaug homolog 2 isoform a
NM_001384574.2 NP_001371503.1 protein Smaug homolog 2 isoform a
NM_001384575.1 NP_001371504.1 protein Smaug homolog 2 isoform a
NM_001384576.1 NP_001371505.1 protein Smaug homolog 2 isoform a
NM_001384577.1 NP_001371506.1 protein Smaug homolog 2 isoform a
NM_001384578.1 NP_001371507.1 protein Smaug homolog 2 isoform a
NM_001384580.1 NP_001371509.1 protein Smaug homolog 2 isoform b
NM_001384581.1 NP_001371510.1 protein Smaug homolog 2 isoform b
NM_001384582.1 NP_001371511.1 protein Smaug homolog 2 isoform b
NM_001384583.1 NP_001371512.1 protein Smaug homolog 2 isoform b
NM_001384584.1 NP_001371513.1 protein Smaug homolog 2 isoform b
NM_001384585.1 NP_001371514.1 protein Smaug homolog 2 isoform c
NM_001384586.1 NP_001371515.1 protein Smaug homolog 2 isoform c
NM_001384587.1 NP_001371516.1 protein Smaug homolog 2 isoform c
NM_001384588.1 NP_001371517.1 protein Smaug homolog 2 isoform c
NM_001384589.1 NP_001371518.1 protein Smaug homolog 2 isoform c
NM_001384590.1 NP_001371519.1 protein Smaug homolog 2 isoform c
NM_001384591.1 NP_001371520.1 protein Smaug homolog 2 isoform c
NM_001384592.1 NP_001371521.1 protein Smaug homolog 2 isoform c
NM_001384593.1 NP_001371522.1 protein Smaug homolog 2 isoform c
NM_001384594.1 NP_001371523.1 protein Smaug homolog 2 isoform c
NM_001384595.1 NP_001371524.1 protein Smaug homolog 2 isoform d
NM_018028.4 NP_060498.2 protein Smaug homolog 2 isoform a

SAMD4B Protein Structure

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (300 - 357)

  • 0
  • 200
  • 400
  • 600
  • 694 a.a.
Protein Preferred Names Protein Names

protein Smaug homolog 2

SAM domain-containing protein 4B

Related Diseases

Diseases Alias
Protoplasmic Astrocytoma

Protoplasmic Astrocytic Tumor

Astrocytoma Protoplasmic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12427 SAMD4B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SAMD4B RGD RGD:1305597
Felis catus SAMD4B VGNC VGNC:64863
Bos taurus SAMD4B VGNC VGNC:34273
Canis familiaris SAMD4B VGNC VGNC:45853
Mus musculus SAMD4B MGD MGI:2448542
Macaca mulatta SAMD4B VGNC VGNC:77102