LARP1B - La ribonucleoprotein 1B Gene
Also Known as LARP2
Species: Homo sapiens
About LARP1B
This gene has 15 transcripts (splice variants), 218 orthologues and 6 paralogues. Broad expression in testis (RPKM 13.1), liver (RPKM 5.0) and 25 other tissues.
Summary
This gene encodes a protein containing domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent Amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and multiple variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined. [provided by RefSeq, Jun 2013]
LARP1B Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001278604.2 | NP_001265533.1 | la-related protein 1B isoform 4 |
| NM_001350531.2 | NP_001337460.1 | la-related protein 1B isoform 5 |
| NM_001410786.1 | NP_001397715.1 | la-related protein 1B isoform 6 |
| NM_018078.4 | NP_060548.2 | la-related protein 1B isoform 1 |
| NM_032239.4 | NP_115615.2 | la-related protein 1B isoform 3 |
| NM_178043.3 | NP_835144.1 | la-related protein 1B isoform 2 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25416956 | GOA |
LARP1B Protein Structure
La: La domain (219 - 276)
- 0
- 200
- 400
- 600
- 800
- 914 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
la-related protein 1B |
|
LARP1B Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
LARP1B | Q659C4 | KIF2A | Homo sapiens | O00139 | 25416956 | |
|
Intra
|
LARP1B | Q659C4 | KIF2A | Homo sapiens | O00139 | 25416956 | |
|
Intra
|
LARP1B | Q659C4 | TRIM69 | Homo sapiens | Q86WT6 | 25416956 |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | LARP1B | MGD | MGI:1914604 |
| Bos taurus | LARP1B | VGNC | VGNC:30791 |
| Canis familiaris | LARP1B | VGNC | VGNC:42588 |
| Rattus norvegicus | LARP1B | RGD | RGD:1307509 |
| Macaca mulatta | LARP1B | VGNC | VGNC:74115 |
| Felis catus | LARP1B | VGNC | VGNC:82486 |
| Others | LARP1B | NCBI |