GOLPH3L - golgi phosphoprotein 3 like Gene

Also Known as GPP34R

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55204

About GOLPH3L

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:150,646,230-150,697,154 (from NCBI)

This gene has 3 transcripts (splice variants), 273 orthologues and 1 paralogue. Ubiquitous expression in colon (RPKM 16.0), thyroid (RPKM 15.0) and 25 other tissues.

Summary

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking. [provided by RefSeq, Jul 2008]

GOLPH3L Products (1)

mRNA Protein Name
NM_018178.6 NP_060648.2 Golgi phosphoprotein 3-like

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cargo adaptor activity IDA
IDA: Inferred from direct assay
34473204 GOA
enables phosphatidylinositol-4-phosphate binding IDA
IDA: Inferred from direct assay
23345592 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
23275563 GOA
Biological Process GO Annotation Evidence References Source
involved in Golgi organization IMP
IMP: Inferred from mutant phenotype
23345592 GOA
involved in positive regulation of protein secretion IMP
IMP: Inferred from mutant phenotype
23345592 GOA
involved in protein targeting to Golgi apparatus IMP
IMP: Inferred from mutant phenotype
34473204 GOA
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
11042173 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GOLPH3L Protein Structure

GPP34

GPP34: Golgi phosphoprotein 3 (GPP34) (48 - 263)

  • 0
  • 100
  • 200
  • 285 a.a.
Protein Preferred Names Protein Names

Golgi phosphoprotein 3-like

  • GPP34-related protein

GOLPH3L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GOLPH3L Q9H4A5 DNM2 Homo sapiens P50570-2
Validated Y2H
32814053
Intra
GOLPH3L Q9H4A5 DNM2 Homo sapiens P50570-2
Y2H Array
32814053
Intra
GOLPH3L Q9H4A5 DNM2 Homo sapiens P50570-2
Y2H Pooling
32814053
Intra
GOLPH3L Q9H4A5 TOR1A Homo sapiens O14656-2
Validated Y2H
32814053
Intra
GOLPH3L Q9H4A5 TOR1A Homo sapiens O14656-2
Y2H Array
32814053
Intra
GOLPH3L Q9H4A5 TOR1A Homo sapiens O14656-2
Y2H Pooling
32814053
Intra
GOLPH3L Q9H4A5 HTT Homo sapiens P42858
Lumier
23275563
Intra
GOLPH3L Q9H4A5 ZDHHC17 Homo sapiens Q8IUH5
Y2H Array
24705354
Intra
GOLPH3L Q9H4A5 ZDHHC17 Homo sapiens Q8IUH5
Lumier
24705354
Intra
GOLPH3L Q9H4A5 LNX1 Homo sapiens Q8TBB1
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05595 GOLPH3L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GOLPH3L MGD MGI:1917129
Bos taurus GOLPH3L VGNC VGNC:29493
Macaca mulatta GOLPH3L VGNC VGNC:73003
Canis familiaris GOLPH3L VGNC VGNC:41346
Rattus norvegicus GOLPH3L RGD RGD:1359281
Felis catus GOLPH3L VGNC VGNC:80223
Others GOLPH3L NCBI