CCDC25 - coiled-coil domain containing 25 Gene

Homo sapiens

Gene ID: 55246 | Gene type: protein coding

About CCDC25

Cytogenetic location: 8p21.1 Genomic coordinates (GRCh38): 8:27,733,316-27,772,640 (from NCBI)

This gene has 11 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in duodenum (RPKM 17.8), small intestine (RPKM 15.9) and 25 other tissues.

Summary

Enables DNA binding activity. Involved in positive regulation of cell motility. Located in endomembrane system. Is integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CCDC25 Products(4)

mRNA	Protein	Name
NM_001304529.2	NP_001291458.1	coiled-coil domain-containing protein 25 isoform 2
NM_001304530.2	NP_001291459.1	coiled-coil domain-containing protein 25 isoform 3
NM_001304532.2	NP_001291461.1	coiled-coil domain-containing protein 25 isoform 4
NM_018246.3	NP_060716.2	coiled-coil domain-containing protein 25 isoform 1

CCDC25 Protein Structure

DUF814

0
100
208 a.a.

Protein Preferred Names

Protein Names

coiled-coil domain-containing protein 25

Related Diseases

Diseases

Alias

Chronic Cholangitis

Colorectal Cancer, Hereditary Nonpolyposis, Type 2

HNPCC2	Fcc2
Coca2	Hereditary Nonpolyposis Colorectal Cancer Type 2
Colon Cancer, Familial Nonpolyposis, Type 2	Familial Nonpolyposis Colon Cancer Type 2
Hereditary Non-Polyposis Colorectal Cancer 2	Cancer, Colorectal, Nonpolyposis, Hereditary, Type 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02041	CCDC25 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CCDC25	MGD	MGI:1914429
Macaca mulatta	CCDC25	VGNC	VGNC:99468
Bos taurus	CCDC25	VGNC	VGNC:26888
Rattus norvegicus	CCDC25	RGD	RGD:1307689
Felis catus	CCDC25	VGNC	VGNC:78463

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