HEMGN - hemogen Gene

Also Known as NDR; EDAG; CT155; EDAG-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55363

About HEMGN

Cytogenetic location: 9q22.33 Genomic coordinates (GRCh38): 9:97,926,791-97,944,852 (from NCBI)

This gene has 2 transcripts (splice variants) and 88 orthologues. Biased expression in bone marrow (RPKM 77.2) and testis (RPKM 23.8).

Summary

Predicted to be involved in regulation of osteoblast differentiation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

HEMGN Products (2)

mRNA Protein Name
NM_018437.5 NP_060907.2 hemogen
NM_197978.3 NP_932095.1 hemogen

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21988832 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hemogen

  • erythroid differentiation-associated gene protein

HEMGN Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
HEMGN Q9BXL5 NPM1 Homo sapiens P06748
Anti Bait CoIP
22712502
Intra
HEMGN Q9BXL5 NPM1 Homo sapiens P06748
IF
22712502
Intra
HEMGN Q9BXL5 NPM1 Homo sapiens P06748
Anti Tag CoIP
22712502
Intra
HEMGN Q9BXL5 CTBP1 Homo sapiens Q13363
Anti Tag CoIP
21988832
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Colorectal Cancer, Hereditary Nonpolyposis, Type 2

  • HNPCC2

  • Fcc2

  • Coca2

  • Hereditary Nonpolyposis Colorectal Cancer Type 2

  • Colon Cancer, Familial Nonpolyposis, Type 2

  • Familial Nonpolyposis Colon Cancer Type 2

  • Hereditary Non-Polyposis Colorectal Cancer 2

  • Cancer, Colorectal, Nonpolyposis, Hereditary, Type 2
Panhypopituitarism, X-Linked

  • PHPX

  • X-Linked Panhypopituitarism

  • Pituitary Dwarfism Iv

  • Panhypopituitarism X-Linked

  • Pituitary Dwarfism Iv, Formerly

  • Panhypopituitarism - X-Linked
Ectodermal Dysplasia 1, Hypohidrotic, X-Linked

  • Christ-Siemens-Touraine Syndrome

  • XHED

  • Ectodermal Dysplasia 1

  • Xlhed

  • Ed1

  • Cst Syndrome

  • Ectodermal Dysplasia 1, Hypohidrotic/Hair/Tooth Type, X-Linked

  • Ectd1

  • Ectodermal Dysplasia, Anhidrotic, X-Linked

  • Eda

  • Eda1

  • Hed1

  • Ectodermal Dysplasia 1, Anhidrotic

  • X-Linked Anhidrotic Ectodermal Dysplasia

  • X-Linked Hypohidrotic Ectodermal Dysplasia

  • Hypohidrotic X-Linked Ectodermal Dysplasia

  • Ectodermal Dysplasia, Hypohidrotic, 1

  • Hypohidrotic Ectodermal Dysplasia, X-Linked

  • Anhidrotic Ectodermal Dysplasia X-Linked

  • Hypohidrotic Ectodermal Dysplasia X-Linked

  • Ectodermal Dysplasia 1 Hypohidrotic/Hair/Tooth Type X-Linked

  • Ectodermal Dysplasia Anhidrotic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta HEMGN VGNC VGNC:73186
Mus musculus HEMGN MGD MGI:2136910
Felis catus HEMGN VGNC VGNC:62793
Bos taurus HEMGN VGNC VGNC:29807
Canis familiaris HEMGN VGNC VGNC:41654
Rattus norvegicus HEMGN RGD RGD:621569
Others HEMGN NCBI