PRB3 - proline rich protein BstNI subfamily 3 Gene

Homo sapiens

Also known as G1; PRG

Gene ID: 5544 | Gene type: protein coding

About PRB3

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:11,265,914-11,269,707 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 4 orthologues and 6 paralogues. Restricted expression toward salivary gland (RPKM 9550.6).

Summary

This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Long" allele. The protein isoforms encoded by this gene are recognized as the "first line of oral defense" against the detrimental effects of Polyphenols in the diet and pathogen infections. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Nov 2015]

PRB3 Products(2)

mRNA	Protein	Name
NM_001394862.1	NP_001381791.1	basic salivary proline-rich protein 3 isoform 2 precursor
NM_006249.5	NP_006240.4	basic salivary proline-rich protein 3 isoform 1 precursor

PRB3 Protein Structure

Pro-rich

0
100
200
309 a.a.

Protein Preferred Names

Protein Names

basic salivary proline-rich protein 3

BstNI type basic salivary proline-rich protein 3

Related Diseases

Diseases

Alias

Head And Neck Cancer

Head And Neck Neoplasm	Head And Neck Tumours
Head/Neck Neoplasm	Tumor Of Head And Neck
Head And Neck Neoplasms	Hnc
Cancer, Head/Neck

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11053	PRB3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PRB3	RGD	RGD:620386