THUMPD1 - THUMP domain containing 1 Gene
Also Known as Tan1; NEDSOA
Species: Homo sapiens
About THUMPD1
This gene has 6 transcripts (splice variants), 213 orthologues and is associated with 1 phenotype. Ubiquitous expression in prostate (RPKM 15.3), endometrium (RPKM 11.9) and 25 other tissues.
Summary
Enables RNA binding activity. Predicted to be involved in tRNA modification. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
THUMPD1 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001304550.2 | NP_001291479.1 | THUMP domain-containing protein 1 |
| NM_017736.5 | NP_060206.2 | THUMP domain-containing protein 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25653167 | GOA |
THUMPD1 Protein Structure
THUMP: THUMP domain (121 - 253)
- 0
- 100
- 200
- 300
- 353 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
THUMP domain-containing protein 1 |
|
THUMPD1 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
THUMPD1 | Q9NXG2 | NAT10 | Homo sapiens | Q9H0A0 | 28514442 | |
|
Intra
|
THUMPD1 | Q9NXG2 | NAT10 | Homo sapiens | Q9H0A0 | 33961781 |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Neurodevelopmental Disorder With Speech Delay And Variable Ocular Anomalies |
|
|
| Noonan Syndrome 1 |
|
|
| Theileriasis |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | THUMPD1 | MGD | MGI:2444479 |
| Rattus norvegicus | THUMPD1 | RGD | RGD:1308854 |
| Bos taurus | THUMPD1 | VGNC | VGNC:35853 |
| Macaca mulatta | THUMPD1 | VGNC | VGNC:99610 |
| Canis familiaris | THUMPD1 | VGNC | VGNC:47360 |
| Others | THUMPD1 | NCBI |