ATF7IP - activating transcription factor 7 interacting protein Gene

Homo sapiens

Also known as AM; MCAF; p621; MCAF1; ATF-IP; ATF7IP1

Gene ID: 55729 | Gene type: protein coding

About ATF7IP

Cytogenetic location: 12p13.1 Genomic coordinates (GRCh38): 12:14,365,682-14,502,930 (from NCBI)

This gene has 24 transcripts (splice variants), 214 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 8.4), testis (RPKM 8.3) and 25 other tissues.

Summary

ATF7IP is a multifunctional nuclear protein that associates with heterochromatin. It can act as a transcriptional coactivator or corepressor depending upon its binding partners (summary by Liu et al., 2009 [PubMed 19106100]).[supplied by OMIM, Nov 2010]

ATF7IP Products(10)

mRNA	Protein	Name
NM_001286514.2	NP_001273443.1	activating transcription factor 7-interacting protein 1 isoform 3
NM_001286515.2	NP_001273444.1	activating transcription factor 7-interacting protein 1 isoform 4
NM_001388179.1	NP_001375108.1	activating transcription factor 7-interacting protein 1 isoform 5
NM_001388180.1	NP_001375109.1	activating transcription factor 7-interacting protein 1 isoform 2
NM_001388181.1	NP_001375110.1	activating transcription factor 7-interacting protein 1 isoform 2
NM_001388182.1	NP_001375111.1	activating transcription factor 7-interacting protein 1 isoform 2
NM_001388183.1	NP_001375112.1	activating transcription factor 7-interacting protein 1 isoform 2
NM_001388184.1	NP_001375113.1	activating transcription factor 7-interacting protein 1 isoform 3
NM_018179.5	NP_060649.3	activating transcription factor 7-interacting protein 1 isoform 2
NM_181352.2	NP_851997.1	activating transcription factor 7-interacting protein 1 isoform 1

Protein Preferred Names

Protein Names

activating transcription factor 7-interacting protein 1

ATF-interacting protein

Related Diseases

Diseases

Alias

Liver Carcinoma In Situ

Carcinoma In Situ Of Liver And Biliary System

Carcinoma In Situ Of Liver, Gallbladder And Bile Ducts

Optic Atrophy 11

OPA11

Atrophy, Optic, Type 11

Uterine Corpus Endometrial Carcinoma

Testicular Germ Cell Cancer

Germ Cell Tumor Of Testis	Testicular Germ Cell Tumor
Testicular Germ Cell Neoplasm	Testicular Malignant Germ Cell Tumor

Alpha Thalassemia-Intellectual Disability Syndrome Type 1

Alpha Thalassemia-Intellectual Disability Syndrome, Deletion Type	Alpha-Thalassemia-Intellectual Disability Syndrome Linked To Chromosome 16
Atr Syndrome Linked To Chromosome 16	Atr Syndrome, Deletion Type
Atr-16 Syndrome	Alpha Thalassemia-Retardation Syndrome
Alpha-Thalassemia/Mental Retardation Syndrome, Deletion-Type	Alpha-Thalassemia/Mental Retardation Syndrome, Type 1
Alpha-Thalassemia Mental Retardation Syndrome, Deletion-Type

Testicular Disease

Testicular Dysfunction	Testicular Diseases
Disorder Of Testis	Testis Disorder
Testicular Disorders

Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism	Undescended Testicle
Undescended Testis	Cryptorchism
Undescended Testicles	CRYPTO
Impaired Testicular Descent	Cryptosporidiosis
Retained Testis	Unilateral Cryptorchidism
Unilateral Undescended Testis	Nondescent Unilateral Testicle
Unilateral Cryptorchism	Ectopic Testis, Unilateral
Bilateral Cryptorchidism	Bilateral Cryptorchism
Bilateral Nondescent Testicle	Bilateral Undescended Testes
Bilateral Ectopic Testes

Testicular Cancer

Testis Cancer	Testicular Carcinoma
Testicular Neoplasms	Malignant Neoplasm Of Testis
Childhood Neoplasm Of The Testis	Neoplasm Of Testis
Pediatric Testicular Neoplasm	Testicular Tumor
Testis Neoplasm	Testicular Tumors
Testicular Neoplasm	Testicular Malignant Germ Cell Tumor
Childhood Testicular Neoplasm	Carcinoma Of The Testis
Cancer Of Testis	Malignant Neoplasm Of Testis, Nos
Malignant Neoplasm Of Testis, Unspecified	Malignant Tumour Of Testis
Testicle Cancer	Primary Malignant Neoplasm Of Testis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01137	ATF7IP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ATF7IP	MGD	MGI:1858965
Felis catus	ATF7IP	VGNC	VGNC:59994
Macaca mulatta	ATF7IP	VGNC	VGNC:70100
Bos taurus	ATF7IP	VGNC	VGNC:26246
Canis familiaris	ATF7IP	VGNC	VGNC:38213
Rattus norvegicus	ATF7IP	RGD	RGD:1306030

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