ZFP64 - ZFP64 zinc finger protein Gene

Also Known as ZNF338

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55734

About ZFP64

Cytogenetic location: 20q13.2 Genomic coordinates (GRCh38): 20:52,084,011-52,191,779 (from NCBI)

This gene has 12 transcripts (splice variants), 214 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 2.7), ovary (RPKM 2.2) and 25 other tissues.

Summary

Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in positive regulation of cytokine production and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of mRNA splicing, via spliceosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZFP64 Products (5)

mRNA Protein Name
NM_001319146.2 NP_001306075.1 zinc finger protein 64 isoform e
NM_018197.3 NP_060667.2 zinc finger protein 64 isoform a
NM_022088.5 NP_071371.3 zinc finger protein 64 isoform b
NM_199426.2 NP_955458.1 zinc finger protein 64 isoform c
NM_199427.3 NP_955459.2 zinc finger protein 64 isoform d

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18430783 GOA
Biological Process GO Annotation Evidence References Source
involved in mesenchymal cell differentiation IMP
IMP: Inferred from mutant phenotype
18430783 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
27353377 GOA
located in megasporocyte nucleus IDA
IDA: Inferred from direct assay
27353377 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZFP64 Protein Structure

zf-C2H2_6

zf-C2H2_6: C2H2-type zinc finger (30 - 56)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (163 - 185)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (190 - 211)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (217 - 240)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (246 - 269)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (273 - 295)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (315 - 337)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (344 - 365)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (371 - 395)

zf-C2H2_6

zf-C2H2_6: C2H2-type zinc finger (425 - 447)

  • 0
  • 200
  • 400
  • 600
  • 681 a.a.
Protein Preferred Names Protein Names

zinc finger protein 64

  • zinc finger protein 338

ZFP64 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZFP64 Q9NTW7 HEL164 Homo sapiens V9HWH0
Validated Y2H
25416956
Intra
ZFP64 Q9NTW7 HEL164 Homo sapiens V9HWH0
Y2H Prey Pooling
25416956
Intra
ZFP64 Q9NTW7 HEL164 Homo sapiens V9HWH0
Y2H Array
25416956
Intra
ZFP64 Q9NTW7 MFAP1 Homo sapiens P55081
Y2H Prey Pooling
25416956
Intra
ZFP64 Q9NTW7 BYSL Homo sapiens Q13895
Y2H Prey Pooling
25416956
Intra
ZFP64 Q9NTW7 BYSL Homo sapiens Q13895
Validated Y2H
25416956
Intra
ZFP64 Q9NTW7 BYSL Homo sapiens Q13895
Y2H Array
25416956
Intra
ZFP64 Q9NTW7 FHL2 Homo sapiens Q14192
Validated Y2H
25416956
Intra
ZFP64 Q9NTW7 FHL2 Homo sapiens Q14192
Y2H Array
31515488
Intra
ZFP64 Q9NTW7 FHL2 Homo sapiens Q14192
Y2H Prey Pooling
25416956
Intra
ZFP64 Q9NTW7 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
ZFP64 Q9NTW7 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
ZFP64 Q9NTW7 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Intra
ZFP64 Q9NTW7 TRIM41 Homo sapiens Q8WV44
Validated Y2H
25416956
Intra
ZFP64 Q9NTW7 TRIM41 Homo sapiens Q8WV44
Y2H Prey Pooling
25416956
Intra
ZFP64 Q9NTW7 TRIM41 Homo sapiens Q8WV44
Y2H Array
25416956
Intra
ZFP64 Q9NTW7 LMO2 Homo sapiens P25791
Y2H Array
25416956
Intra
ZFP64 Q9NTW7 LNX1 Homo sapiens Q8TBB1
Y2H Array
29892012
Intra
ZFP64 Q9NTW7 LNX1 Homo sapiens Q8TBB1
Validated Y2H
25416956
Intra
ZFP64 Q9NTW7 LNX1 Homo sapiens Q8TBB1
Y2H Prey Pooling
25416956
Intra
ZFP64 Q9NTW7 FAM124A Homo sapiens Q86V42
Y2H Prey Pooling
25416956
Intra
ZFP64 Q9NTW7 AEN Homo sapiens Q8WTP8
Validated Y2H
25416956
Intra
ZFP64 Q9NTW7 AEN Homo sapiens Q8WTP8
Y2H
21516116
Intra
ZFP64 Q9NTW7 AEN Homo sapiens Q8WTP8
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16045 ZFP64 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ZFP64 VGNC VGNC:37167
Felis catus ZFP64 VGNC VGNC:81264
Macaca mulatta ZFP64 VGNC VGNC:78994
Canis familiaris ZFP64 VGNC VGNC:48616
Rattus norvegicus ZFP64 RGD RGD:1307948
Mus musculus ZFP64 MGD MGI:107342
Others ZFP64 NCBI