ZC3H15 - zinc finger CCCH-type containing 15 Gene

Also Known as DFRP1; HT010; LEREPO4; MSTP012

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55854

About ZC3H15

Cytogenetic location: 2q32.1 Genomic coordinates (GRCh38): 2:186,486,260-186,509,361 (from NCBI)

This gene has 9 transcripts (splice variants) and 233 orthologues. Ubiquitous expression in bone marrow (RPKM 44.3), brain (RPKM 30.6) and 25 other tissues.

Summary

Enables RNA binding activity and Cadherin binding activity. Involved in positive regulation of GTPase activity. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

ZC3H15 Products (1)

mRNA Protein Name
NM_018471.3 NP_060941.2 zinc finger CCCH domain-containing protein 15

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19819225 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of GTPase activity IDA
IDA: Inferred from direct assay
23711155 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZC3H15 Protein Structure

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (100 - 124)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 426 a.a.
Protein Preferred Names Protein Names

zinc finger CCCH domain-containing protein 15

  • DRG family-regulatory protein 1

ZC3H15 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZC3H15 Q8WU90 DRG1 Homo sapiens Q9Y295
Validated Y2H
25416956
Intra
ZC3H15 Q8WU90 DRG1 Homo sapiens Q9Y295
Validated Y2H
32296183
Intra
ZC3H15 Q8WU90 DRG1 Homo sapiens Q9Y295
Y2H
21516116
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15990 ZC3H15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ZC3H15 VGNC VGNC:79812
Bos taurus ZC3H15 VGNC VGNC:37103
Canis familiaris ZC3H15 VGNC VGNC:48556
Rattus norvegicus ZC3H15 RGD RGD:1359234
Mus musculus ZC3H15 MGD MGI:1919747
Felis catus ZC3H15 VGNC VGNC:67184