ACTR10 - actin related protein 10 Gene

Also Known as Arp10; Arp11; ACTR11; HARP11

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55860

About ACTR10

Cytogenetic location: 14q23.1 Genomic coordinates (GRCh38): 14:58,200,149-58,235,636 (from NCBI)

This gene has 16 transcripts (splice variants), 214 orthologues and 26 paralogues. Ubiquitous expression in brain (RPKM 22.5), adrenal (RPKM 21.9) and 25 other tissues.

Summary

Predicted to be involved in retrograde axonal transport of mitochondrion. Predicted to be located in cytosol; extracellular region; and secretory granule. Predicted to be part of dynactin complex. [provided by Alliance of Genome Resources, Apr 2022]

ACTR10 Products (1)

mRNA Protein Name
NM_018477.3 NP_060947.1 actin-related protein 10

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ACTR10 Protein Structure

Actin

Actin: Actin (11 - 383)

  • 0
  • 100
  • 200
  • 300
  • 417 a.a.
Protein Preferred Names Protein Names

actin-related protein 10

  • actin related protein 10 homolog

ACTR10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ACTR10 Q9NZ32 DCTN4 Homo sapiens Q9UJW0
Validated Y2H
32296183
Intra
ACTR10 Q9NZ32 NAGK Homo sapiens Q9UJ70
Validated Y2H
25416956
Intra
ACTR10 Q9NZ32 NAGK Homo sapiens Q9UJ70
Y2H Array
25416956
Intra
ACTR10 Q9NZ32 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
ACTR10 Q9NZ32 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Brachydactyly, Type A3

  • Brachydactyly Type A3

  • BDA3

  • Brachydactyly-Clinodactyly

  • Brachymesophalangy V

  • Brachymesophalangy 5

  • Brachydactyly Clinodactyly
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00227 ACTR10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ACTR10 MGD MGI:1891654
Canis familiaris ACTR10 VGNC VGNC:37551
Rattus norvegicus ACTR10 RGD RGD:1306515
Macaca mulatta ACTR10 VGNC VGNC:69449
Felis catus ACTR10 VGNC VGNC:104354
Bos taurus ACTR10 VGNC VGNC:25584
Others ACTR10 NCBI