NAGK - N-acetylglucosamine kinase Gene

Also Known as GNK; HSA242910

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55577

About NAGK

Cytogenetic location: 2p13.3 Genomic coordinates (GRCh38): 2:71,068,296-71,079,808 (from NCBI)

This gene has 29 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in spleen (RPKM 27.6), esophagus (RPKM 26.3) and 25 other tissues.

Summary

This gene encodes a member of the N-acetylhexosamine kinase family. The encoded protein catalyzes the conversion of N-acetyl-D-glucosamine to N-acetyl-D-glucosamine 6-phosphate, and is the major mammalian enzyme which recovers amino sugars. [provided by RefSeq, Nov 2011]

NAGK Products (4)

mRNA Protein Name
NM_001330425.3 NP_001317354.1 N-acetyl-D-glucosamine kinase isoform 2
NM_001330426.2 NP_001317355.1 N-acetyl-D-glucosamine kinase isoform 2
NM_001365466.2 NP_001352395.1 N-acetyl-D-glucosamine kinase isoform 2
NM_017567.6 NP_060037.4 N-acetyl-D-glucosamine kinase isoform 1

NAGK Protein Structure

BcrAD_BadFG

BcrAD_BadFG: BadF/BadG/BcrA/BcrD ATPase family (7 - 278)

  • 0
  • 100
  • 200
  • 300
  • 344 a.a.
Protein Preferred Names Protein Names

N-acetyl-D-glucosamine kinase

  • epididymis secretory sperm binding protein

NAGK Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NAGK Q9UJ70 ACTR10 Homo sapiens Q9NZ32
Y2H Prey Pooling
25416956
Intra
NAGK Q9UJ70 MEOX1 Homo sapiens P50221
Y2H Array
25416956
Intra
NAGK Q9UJ70 MEOX1 Homo sapiens P50221
Y2H Prey Pooling
25416956
Intra
NAGK Q9UJ70 REL Homo sapiens Q04864
Validated Y2H
25416956
Intra
NAGK Q9UJ70 REL Homo sapiens Q04864
Y2H Array
25416956
Intra
NAGK Q9UJ70 DACH1 Homo sapiens Q9UI36
Y2H
21516116
Intra
NAGK Q9UJ70 CDKN2C Homo sapiens P42773
Y2H Array
31515488
Intra
NAGK Q9UJ70 CDKN2C Homo sapiens P42773
Y2H Prey Pooling
25416956
Intra
NAGK Q9UJ70 CDKN2C Homo sapiens P42773
Validated Y2H
25416956
Intra
NAGK Q9UJ70 TCF12 Homo sapiens Q99081
Validated Y2H
25416956
Intra
NAGK Q9UJ70 SDCBP Homo sapiens O00560
Y2H Prey Pooling
25416956
Intra
NAGK Q9UJ70 SDCBP Homo sapiens O00560
Validated Y2H
25416956
Intra
NAGK Q9UJ70 LNX1 Homo sapiens Q8TBB1
Pull Down
16189514
Intra
NAGK Q9UJ70 LNX1 Homo sapiens Q8TBB1
Y2H Array
29892012
Intra
NAGK Q9UJ70 LNX1 Homo sapiens Q8TBB1
Y2H Pooling
16189514
Cross
NAGK Q9UJ70 Snrpn Rattus norvegicus P63164
Anti Tag CoIP
37511433
Cross
NAGK Q9UJ70 Snrpn Rattus norvegicus P63164
Pull Down
37511433
Cross: Cross-species interaction Intra: Intraspecies interaction

NAGK Antibodies

Cat. No. Product Name Application Reactivity
HY-P89717 GlcNAc kinase Antibody (YA9061) WB, ICC/IF, IF-Tissue, IP, ELISA human

Related Diseases

Diseases Alias
Nonaka Myopathy

  • Gne Myopathy

  • Hibm

  • Distal Myopathy With Rimmed Vacuoles

  • Hereditary Inclusion Body Myopathy

  • Ibm2

  • Inclusion Body Myopathy, Quadriceps-Sparing

  • Qsm

  • Dmrv

  • Distal Myopathy, Nonaka Type

  • Inclusion Body Myopathy 2

  • Inclusion Body Myopathy, Autosomal Recessive

  • NM

  • Nonaka Distal Myopathy

  • Myopathy, Distal, With Or Without Rimmed Vacuoles

  • Inclusion Body Myopathy, Hereditary, Autosomal Recessive

  • Inclusion Body Myopathy Type 2

  • Quadriceps-Sparing Myopathy

  • Quadriceps Sparing Myopathy

  • Rimmed Vacuole Myopathy

  • Inclusion Body Myopathy 2, Autosomal Recessive, Formerly

  • Ibm2, Formerly

  • Hibm2

  • Hereditary Inclusion Body Myopathy Type 2

  • Inclusion Body Myopathy 2, Autosomal Recessive

  • Myopathy, Distal, With Rimmed Vacuoles

  • Inclusion Body Myopathy Autosomal Recessive

  • Myopathy, Inclusion Body, Type 2

  • Myopathy, Nonaka
Sialuria

  • Sialuria, French Type

  • French Type Sialuria

  • Sialuria French Type

  • Sialic Acid Storage Disease

  • Sialic Acid Storage Disease, Finnish Type

  • Infantile Sialic Acid Storage Disease
Chronic Monocytic Leukemia

  • Leukemia, Myeloid

  • Leukemia, Monocytic, Chronic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-177554 KB05yne 99.97% Unkown
HY-185414 KB05-Biotin / Unkown
HY-180637 N-Acetyl-L-glutamate 5-phosphate / Unkown
HY-RS09010 NAGK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20780 Nagk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27294 Nagk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus NAGK RGD RGD:1305057
Macaca mulatta NAGK VGNC VGNC:74977
Bos taurus NAGK VGNC VGNC:31868
Mus musculus NAGK MGD MGI:1860418
Felis catus NAGK VGNC VGNC:63713
Others NAGK NCBI