Vps29 - VPS29 retromer complex component Gene

Also Known as PEP11; 2010015D08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56433

Summary

Predicted to enable metal ion binding activity. Predicted to be involved in endocytic recycling; intracellular protein transport; and retrograde transport, endosome to Golgi. Predicted to act upstream of or within Golgi to vacuole transport. Part of retromer complex. Is expressed in cranial ganglion; dorsal root ganglion; and gonad. Orthologous to human VPS29 (VPS29 retromer complex component). [provided by Alliance of Genome Resources, Apr 2022]

Vps29 Products (3)

mRNA Protein Name
NM_001347453.2 NP_001334382.1 vacuolar protein sorting-associated protein 29 isoform 1
NM_001359226.1 NP_001346155.1 vacuolar protein sorting-associated protein 29 isoform 3
NM_019780.2 NP_062754.1 vacuolar protein sorting-associated protein 29 isoform 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15965486 MGI
Cellular Component GO Annotation Evidence References Source
part of retromer complex IDA
IDA: Inferred from direct assay
21040701 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein 29

  • vacuolar protein sorting 29

  • vacuolar sorting protein 29

  • vesicle protein sorting 29

Vps29 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Vps29 Q9QZ88 VPS35 Homo sapiens Q96QK1
Anti Tag CoIP
20923837
Cross
Vps29 Q9QZ88 FKBP15 Homo sapiens Q5T1M5
Y2H
20923837
Cross
Vps29 Q9QZ88 FKBP15 Homo sapiens Q5T1M5
Anti Tag CoIP
20923837
Cross
Vps29 Q9QZ88 TBC1D5 Homo sapiens Q92609
Anti Tag CoIP
20923837
Intra
Vps29 Q9QZ88 Vps35 Mus musculus Q9EQH3
Y2H
20923837
Intra
Vps29 Q9QZ88 Vps35 Mus musculus Q9EQH3
Anti Bait CoIP
21040701
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15682 VPS29 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22915 Vps29 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29429 Vps29 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps29 NCBI NCBI:51699