ZNF350 - zinc finger protein 350 Gene

Also Known as ZFQR; ZBRK1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 59348

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nuclear body. Part of transcription repressor complex. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in prostate (RPKM 10.8), thyroid (RPKM 4.3) and 24 other tissues.

ZNF350 Products (1)

mRNA Protein Name
NM_021632.4 NP_067645.3 zinc finger protein 350

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
11090615 GOA
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
11090615 GOA
enables RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11090615 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
11090615 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11090615 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11090615 GOA
involved in regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11090615 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
23665872 GOA
part of transcription repressor complex IDA
IDA: Inferred from direct assay
11090615 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF350 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF350 Q9GZX5 BRCA1 Homo sapiens P38398
Pull Down
11090615
Intra
ZNF350 Q9GZX5 BRCA1 Homo sapiens P38398
CoIP
11090615
Intra
ZNF350 Q9GZX5 TRIM28 Homo sapiens Q13263
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16173 ZNF750 Human Pre-designed siRNA Set A Pre-designed Set / Unkown