Stx6 - syntaxin 6 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60562

Summary

Predicted to enable SNAP receptor activity and syntaxin binding activity. Involved in synaptic vesicle to endosome fusion. Located in synaptic vesicle and trans-Golgi network membrane. Is integral component of membrane. Is integral component of synaptic vesicle membrane. Orthologous to human STX6 (syntaxin 6). [provided by Alliance of Genome Resources, Apr 2022]

Stx6 Products (1)

mRNA Protein Name
NM_031665.2 NP_113853.1 syntaxin-6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9243506 RGD
Biological Process GO Annotation Evidence References Source
involved in endocytic recycling IDA
IDA: Inferred from direct assay
30962439 RGD
involved in retrograde transport, endosome to Golgi IDA
IDA: Inferred from direct assay
30962439 RGD
involved in synaptic vesicle to endosome fusion IDA
IDA: Inferred from direct assay
17004320 RGD
involved in synaptic vesicle to endosome fusion IMP
IMP: Inferred from mutant phenotype
17004320 RGD
involved in vesicle-mediated transport IDA
IDA: Inferred from direct assay
8663448 RGD
Cellular Component GO Annotation Evidence References Source
located in recycling endosome IDA
IDA: Inferred from direct assay
30962439 RGD
is active in synaptic vesicle membrane EXP
EXP: Inferred from Experiment
17110340 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
17004320 RGD
located in trans-Golgi network membrane IDA
IDA: Inferred from direct assay
9243506 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

syntaxin-6

  • Syn6

Stx6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Stx6 Q63635 EEA1 Homo sapiens Q15075
Anti Tag CoIP
10506127
Cross
Stx6 Q63635 EEA1 Homo sapiens Q15075
Y2H
10506127
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13986 STX6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20341 Stx6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26849 Stx6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stx6 NCBI NCBI:10228