CCL14 - C-C motif chemokine ligand 14 Gene

Homo sapiens

Also known as CC-1; CC-3; CKB1; MCIF; NCC2; SY14; HCC-1; HCC-3; NCC-2; SCYL2; SCYA14; HCC-1(1-74); HCC-1/HCC-3

Gene ID: 6358 | Gene type: protein coding

About CCL14

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:35,983,288-35,986,729 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 141 orthologues and 25 paralogues. Broad expression in spleen (RPKM 229.5), fat (RPKM 134.4) and 15 other tissues.

Summary

This gene, chemokine (C-C motif) ligand 14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and Enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene, chemokine (C-C motif) ligand 15, and are represented as GeneID: 348249. [provided by RefSeq, Dec 2009]

CCL14 Products(2)

mRNA	Protein	Name
NM_032962.5	NP_116738.1	C-C motif chemokine 14 isoform 2 precursor
NM_032963.4	NP_116739.1	C-C motif chemokine 14 isoform 1 precursor

CCL14 Protein Structure

IL8

0
100
115 a.a.

Protein Preferred Names

Protein Names

C-C motif chemokine 14

chemokine (C-C motif) ligand 14

Recombinant CCL14 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7195	HCC-1/CCL14 Protein, Human	Q16627 (T22-N93)	≥95%
HY-P7763	HCC-1/CCL14 Protein, Human (HEK293, His)	Q16627 (T20-N93)	≥95%
HY-P75148	HCC-1/CCL14 Protein, Human (74a.a, His)	Q16627 (T20-N93)	≥95%
HY-P75149	HCC-1/CCL14 Protein, Human (66a.a, His)	Q16627 (G28-N93)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02083	CCL14 Human Pre-designed siRNA Set A		/	Unkown

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