CCL16 - C-C motif chemokine ligand 16 Gene

Homo sapiens

Also known as LEC; LMC; NCC4; CKb12; HCC-4; LCC-1; Mtn-1; NCC-4; SCYL4; ILINCK; SCYA16

Gene ID: 6360 | Gene type: protein coding

About CCL16

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:35,976,499-35,981,497 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 91 orthologues and 25 paralogues. Biased expression in liver (RPKM 21.1) and spleen (RPKM 0.6).

Summary

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10. [provided by RefSeq, Jul 2008]

CCL16 Products(1)

mRNA	Protein	Name
NM_004590.4	NP_004581.1	C-C motif chemokine 16 precursor

CCL16 Protein Structure

IL8

0
100
120 a.a.

Protein Preferred Names

Protein Names

C-C motif chemokine 16

IL-10-inducible chemokine

Recombinant CCL16 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7196	HCC-4/CCL16 Protein, Human (CHO)	O15467 (Q24-Q120)	≥95%
HY-P7197	HCC-4/CCL16 Protein, Human	O15467 (Q24-Q120)	≥95%
HY-P72760	HCC-4/CCL16 Protein, Human-1	O15467 (Q24-Q120)	≥95%

Related Diseases

Diseases

Alias

Ring Dermoid Of Cornea

RDC	Ring Dermoid Syndrome
Bilateral, Annular Limbal Dermoids With Corneal And Conjunctival Extension	Dermoid Of Cornea, Ring

Cataract 18

Cataract, Autosomal Recessive Congenital 2	Catc2
CTRCT18	Autosomal Recessive Congenital Cataract 2
Cataract 18, Autosomal Recessive	Cataract 18 Autosomal Recessive
Cataract, Type 18

Leber Congenital Amaurosis 1

LCA1	Amaurosis Congenita Of Leber I
Lca	Retinal Blindness, Congenital
Crb	Leber Congenital Amaurosis Type I
Leber Congenital Amaurosis, Type 1	Amaurosis Congenita Of Leber, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02085	CCL16 Human Pre-designed siRNA Set A		/	Unkown

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