FKBPL - FKBP prolyl isomerase like Gene

Also Known as NG7; DIR1; WISP39

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 63943

About FKBPL

Cytogenetic location: 6p21.32 Genomic coordinates (GRCh38): 6:32,128,707-32,130,288 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 175 orthologues and 18 paralogues. Ubiquitous expression in skin (RPKM 3.5), thyroid (RPKM 3.5) and 25 other tissues.

Summary

The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle. [provided by RefSeq, Jul 2008]

FKBPL Products (1)

mRNA Protein Name
NM_022110.4 NP_071393.2 FK506-binding protein-like

FKBPL Protein Structure

TPR_11

TPR_11: TPR repeat (209 - 283)

TPR_1

TPR_1: Tetratricopeptide repeat (287 - 319)

  • 0
  • 100
  • 200
  • 300
  • 349 a.a.
Protein Preferred Names Protein Names

FK506-binding protein-like

  • FK506 binding protein like

FKBPL Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FKBPL Q9UIM3 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
25416956
Intra
FKBPL Q9UIM3 CALCOCO2 Homo sapiens Q13137
Validated Y2H
25416956
Intra
FKBPL Q9UIM3 ANKRD49 Homo sapiens Q8WVL7
Y2H Prey Pooling
32296183
Intra
FKBPL Q9UIM3 ANKRD49 Homo sapiens Q8WVL7
Y2H Array
32296183
Intra
FKBPL Q9UIM3 ANKRD49 Homo sapiens Q8WVL7
Anti Tag CoIP
25036637
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Abnormal Retinal Correspondence
Tolosa-Hunt Syndrome

  • Painful Ophthalmoplegia

  • Tolosa Hunt Syndrome

  • Nonspecific Inflammation Of The Cavernous Sinus Or Superior Orbital Fissure

  • Ths

  • Ophthalmoplegia, Painful
Spermatogenic Failure, Y-Linked, 2

  • SPGFY2

  • Spermatogenic Failure, Nonobstructive, Y-Linked

  • Y-Linked Spermatogenic Failure 2

  • Azoospermia, Nonobstructive, Y-Linked

  • Oligozoospermia, Nonobstructive, Y-Linked

  • Oligospermia, Nonobstructive, Y-Linked

  • Spermatogenic Arrest, Y-Linked

  • Nonobstructive Y-Linked Spermatogenic Failure

  • Spermatogenic Failure Y-Linked 2

  • Azoospermia Non-Obstructive Y-Linked

  • Non-Obstructive Azoospermia And Infertility

  • Oligospermia Non-Obstructive Y-Linked

  • Oligozoospermia Non-Obstructive Y-Linked

  • Spermatogenic Arrest Y-Linked

  • Spermatogenic Failure Nonobstructive Y-Linked
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P2284 AD 01 Ligand 99.98% Unkown
HY-RS04970 FKBPL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus FKBPL MGD MGI:1932127
Bos taurus FKBPL VGNC VGNC:29028
Felis catus FKBPL VGNC VGNC:62286
Macaca mulatta FKBPL VGNC VGNC:72506
Rattus norvegicus FKBPL RGD RGD:1303227
Others FKBPL NCBI