SUDS3 - SIN3A corepressor complex component SDS3 Gene

Also Known as SDS3; SAP45

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64426

Summary

SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]
Ubiquitous expression in thyroid (RPKM 8.3), testis (RPKM 7.0) and 25 other tissues.

SUDS3 Products (1)

mRNA Protein Name
NM_022491.3 NP_071936.2 sin3 histone deacetylase corepressor complex component SDS3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
21239494 GOA
contributes to histone deacetylase activity IDA
IDA: Inferred from direct assay
21239494 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
12670868 GOA
Biological Process GO Annotation Evidence References Source
involved in chromatin remodeling IDA
IDA: Inferred from direct assay
21239494 GOA
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
22783022 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
21239494 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SUDS3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SUDS3 Q9H7L9 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
SUDS3 Q9H7L9 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
SUDS3 Q9H7L9 LDOC1 Homo sapiens O95751
Y2H Prey Pooling
32296183
Intra
SUDS3 Q9H7L9 LDOC1 Homo sapiens O95751
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14048 SUSD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22840 Susd3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29355 Susd3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown