FAM83G - family with sequence similarity 83 member G Gene

Also Known as PAWS1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 644815

About FAM83G

Cytogenetic location: 17p11.2 Genomic coordinates (GRCh38): 17:18,968,789-19,006,116 (from NCBI)

This gene has 4 transcripts (splice variants), 271 orthologues and 7 paralogues. Biased expression in skin (RPKM 27.6), esophagus (RPKM 12.8) and 13 other tissues.

Summary

Predicted to enable protein kinase binding activity. Involved in BMP signaling pathway. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

FAM83G Products (1)

mRNA Protein Name
NM_001039999.3 NP_001035088.2 protein FAM83G

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23455922 GOA
Biological Process GO Annotation Evidence References Source
involved in BMP signaling pathway IDA
IDA: Inferred from direct assay
24554596 GOA
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
24554596 GOA
located in nucleus IDA
IDA: Inferred from direct assay
24554596 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FAM83G Protein Structure

DUF1669

DUF1669: Protein of unknown function (DUF1669) (9 - 310)

  • 0
  • 200
  • 400
  • 600
  • 823 a.a.
Protein Preferred Names Protein Names

protein FAM83G

  • protein associated with SMAD1

FAM83G Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FAM83G A6ND36 CSNK1A1 Homo sapiens P48729
Protein Kinase Assay
29789297
Intra
FAM83G A6ND36 CSNK1A1 Homo sapiens P48729
Anti Tag CoIP
29789297
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Amelogenesis Imperfecta, Type Iiia

  • Ai3

  • Adhcai

  • Amelogenesis Imperfecta Type 3

  • AI3A

  • Amelogenesis Imperfecta, Type Iii

  • Amelogenesis Imperfecta, Hypocalcification Type, Autosomal Dominant

  • Amelogenesis Imperfecta Type 3a

  • Amelogenesis Imperfecta Hypomineralization Type

  • Amelogenesis Imperfecta Type Iii

  • Hypocalcified Amelogenesis Imperfecta

  • Amelogenesis Imperfecta, Type 3

  • Amelogenesis Imperfecta, Hypomineralization Type

  • Autosomal Dominant Amelogenesis Imperfecta Hypocalcification Type

  • Amelogenesis Imperfecta 3a

  • Amelogenesis Imperfecta Hypocalcification Type Autosomal Dominant
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04725 FAM83G Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus FAM83G VGNC VGNC:62133
Rattus norvegicus FAM83G RGD RGD:2322345
Canis familiaris FAM83G VGNC VGNC:40704
Macaca mulatta FAM83G VGNC VGNC:99150
Bos taurus FAM83G VGNC VGNC:28838
Mus musculus FAM83G MGD MGI:1916890
Others FAM83G NCBI