Dlgap1 - DLG associated protein 1 Gene

Also Known as Gkap; DAP-1; rGKAP; SAPAP1; GKAP/SAPAP1

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 65040

Summary

Enables protein domain specific binding activity. A structural constituent of postsynaptic density. Involved in aggresome assembly; protein localization to synapse; and regulation of proteasomal protein catabolic process. Located in postsynaptic density and postsynaptic membrane. Is active in glutamatergic synapse and postsynaptic density, intracellular component. Orthologous to human DLGAP1 (DLG associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Dlgap1 Products (2)

mRNA	Protein	Name
NM_001304287.1	NP_001291216.1	disks large-associated protein 1 isoform 2
NM_022946.3	NP_075235.3	disks large-associated protein 1 isoform 1

Protein Preferred Names	Protein Names
disks large-associated protein 1	PSD-95 binding protein PSD-95/SAP90-binding protein 1 SAP90/PSD-95-associated protein 1 discs large homolog associated protein 1 guanylate kinase-associated protein

Dlgap1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	Dlgap1	P97836	Dlg4	Rattus norvegicus	P31016	Anti Bait CoIP	10433268
Intra	Dlgap1	P97836	Dlg4	Rattus norvegicus	P31016	Y2H	9694864
Intra	Dlgap1	P97836	Dlg4	Rattus norvegicus	P31016	Anti Tag CoIP	9115257
Intra	Dlgap1	P97836	Dlg4	Rattus norvegicus	P31016	Y2H	9115257
Intra	Dlgap1	P97836	Dlg4	Rattus norvegicus	P31016	Filter Binding	9694864
Intra	Dlgap1	P97836	Magi2	Rattus norvegicus	O88382	Filter Binding	9694864
Intra	Dlgap1	P97836	Shank1	Rattus norvegicus	Q9WV48	CoIP	10488079
Intra	Dlgap1	P97836	Shank1	Rattus norvegicus	Q9WV48	IF	11583995
Intra	Dlgap1	P97836	Shank1	Rattus norvegicus	Q9WV48	Anti Bait CoIP	10433268
Intra	Dlgap1	P97836	Shank1	Rattus norvegicus	Q9WV48	Anti Bait CoIP	11178875

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03801	DLGAP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dlgap1	NCBI	NCBI:9229