Necap1 - NECAP endocytosis associated 1 Gene

Also Known as 1200016B17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67602

Summary

Involved in endocytosis. Located in clathrin-coated pit. Part of clathrin vesicle coat. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 21. Orthologous to human NECAP1 (NECAP endocytosis associated 1). [provided by Alliance of Genome Resources, Apr 2022]

Necap1 Products (1)

mRNA Protein Name
NM_026267.3 NP_080543.2 adaptin ear-binding coat-associated protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
14555962 MGI
Biological Process GO Annotation Evidence References Source
involved in endocytosis IMP
IMP: Inferred from mutant phenotype
14555962 MGI
Cellular Component GO Annotation Evidence References Source
part of clathrin vesicle coat IDA
IDA: Inferred from direct assay
14555962 MGI
located in clathrin-coated pit IDA
IDA: Inferred from direct assay
14555962 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adaptin ear-binding coat-associated protein 1

  • NECAP endocytosis-associated protein 1

  • brain enriched NECAP2 similar protein

  • clathrin-coated vesicle coat protein

  • snoRNA MBI-129

Necap1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Necap1 Q9CR95 SNAP91 Homo sapiens O60641
Pull Down
17762867
Intra
Necap1 Q9CR95 Dab2 Mus musculus P98078
Pull Down
17762867
Intra
Necap1 Q9CR95 Fcho1 Mus musculus Q8K285
Pull Down
24130457
Cross
Necap1 Q9CR95 AMPH Homo sapiens P49418
Pull Down
17762867
Cross
Necap1 Q9CR95 AMPH Homo sapiens P49418
Competition Binding
17762867
Cross
Necap1 Q9CR95 Amph Rattus norvegicus O08838
Pull Down
17762867
Cross
Necap1 Q9CR95 Amph Rattus norvegicus O08838
Pull Down
24130457
Cross
Necap1 Q9CR95 Bin1 Rattus norvegicus O08839
Pull Down
24130457
Cross
Necap1 Q9CR95 Bin1 Rattus norvegicus O08839
Pull Down
17762867
Cross
Necap1 Q9CR95 Bin1 Rattus norvegicus O08839
Competition Binding
17762867
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09172 NECAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Necap1 NCBI NCBI:25977