Cdk3 - cyclin-dependent kinase 3 Gene

Also Known as Cdk3-ps; 2310050O10Rik

Species: Mus musculus

Gene Type: pseudo
Gene ID: 69681

About Cdk3

Chromosome 11: 116,106,829-116,111,113 forward strand.GRCm39:CM001004.3

This gene has 3 transcripts (splice variants), 121 orthologues and 25 paralogues. Ubiquitous expression in limb E14.5 (RPKM 2.3), whole brain E14.5 (RPKM 2.2) and 27 other tissues.

Summary

Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to be active in nucleus. Is expressed in several structures, including chondrocranium; heart; hindbrain roof; lung; and nasal cavity. Orthologous to human CDK3 (cyclin dependent kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Cdk3 Products (4)

mRNA Protein Name
AK009918.1 BAB26584.1 unnamed protein product (C57BL/6J)
AK166387.1 BAE38746.1 unnamed protein product, partial
BC116895.1 None
BC119034.1 None

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1165 Cyproheptadine (hydrochloride sesquihydrate) 99.74% Unkown

Clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Phase
HY-X0009 Tambiciclib Inhibitor 99.68% Phase 2
HY-137478 KB-0742 Inhibitor 99.63% Phase 2
HY-137478A KB-0742 dihydrochloride Inhibitor 98.77% Phase 2
HY-X0009A Tambiciclib dimaleate Inhibitor 99.53% Phase 2
HY-10014 R547 Inhibitor 99.57% Phase 1
HY-12871B Atuveciclib Inhibitor 99.75% Phase 1
HY-15504 RGB-286638 Inhibitor 99.67% Phase 1
HY-137443 Ipivivint Inhibitor 99.95% Phase 1
HY-15504A RGB-286638 free base Inhibitor 98.09% Phase 1

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-10329 JNJ-7706621 Inhibitor 99.39% Unkown
HY-15951 ML167 Inhibitor 98.62% Unkown
HY-119940 MC180295 Inhibitor 98.07% Unkown
HY-N9561 Vanicoside B Inhibitor 99.82% Unkown
HY-15241 NVP-LCQ195 Inhibitor 98.88% Unkown
HY-185121 PROTAC CDK2/4/6 Degrader-2 Degrader 97.22% Unkown
HY-142696 CDK6/PIM1-IN-1 Inhibitor / Unkown
HY-163856 CDK7-IN-30 Inhibitor / Unkown
HY-137478B KB-0742 hydrochloride Inhibitor / Unkown
HY-151878 CDK7-IN-20 Inhibitor / Unkown
HY-182470 AG-012986 dihydrochloride Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdk3 NCBI NCBI:1018