Ecd - ecdysoneless cell cycle regulator Gene

Also Known as Hsgt1; 5730461K03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 70601

Summary

Predicted to enable Histone Acetyltransferase binding activity. Acts upstream of or within cell population proliferation and regulation of G1/S transition of mitotic cell cycle. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in 1st branchial arch; genitourinary system; and maxillary process. Orthologous to human ECD (ecdysoneless cell cycle regulator). [provided by Alliance of Genome Resources, Apr 2022]

Ecd Products (1)

mRNA Protein Name
NM_027475.3 NP_081751.1 protein ecdysoneless homolog

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18474241 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within fibroblast proliferation IMP
IMP: Inferred from mutant phenotype
19640839 MGI
acts upstream of or within regulation of G1/S transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
19640839 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein ecdysoneless homolog

  • ecdysoneless homolog

  • protein SGT1 homolog

  • suppressor of S. cerevisiae gcr2

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99380 Zanidatamab Inhibitor 98.56% Unkown

Clinical Phase

Bioactive MoleculesInhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Phase
HY-P991332 JAB-BX102 Inhibitor / Phase 2
HY-P991572 MM-151 Antagonist / Phase 2
HY-P991330 BMS-986179 Inhibitor / Phase 2
HY-P991443 IPH5301 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18377 Bioymifi 98.00% Unkown
HY-P10495 GPR110 peptide agonist P12 Activator / Unkown
HY-RS04132 ECD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12649 SEM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-B0828S Triazophos-d5 Inhibitor / Unkown
HY-RS17935 Ecd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24405 Ecd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990957 Ficerafusp alfa Inhibitor 99.71% Unkown
HY-P990903 Avitotamig Inhibitor 95.98% Unkown
HY-P99963 Sudubrilimab Inhibitor ≥99.0% Unkown
HY-P991239 NM-02 Inhibitor / Unkown
HY-P991465 Anti-CD27 Antibody (M2177) Inhibitor / Unkown
HY-P991466 Anti-CD27 Antibody (M2191) Inhibitor / Unkown
HY-P992341 D8P1C1 Inhibitor / Unkown
HY-P992481 VERT-002 Degrader / Unkown
HY-P991331 BC-010 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ecd NCBI NCBI:11319