CCDC61 - coiled-coil domain containing 61 Gene

Also Known as VFL3; hVFL3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 729440

Summary

Enables identical protein binding activity and microtubule binding activity. Involved in centriole assembly and mitotic spindle assembly. Located in centriolar satellite and ciliary basal body. Part of centriolar subdistal appendage. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in testis (RPKM 2.6), spleen (RPKM 1.6) and 25 other tissues.

CCDC61 Products (1)

mRNA Protein Name
NM_001267723.2 NP_001254652.1 centrosomal protein CCDC61

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IMP
IMP: Inferred from mutant phenotype
32375023 GOA
enables microtubule binding IMP
IMP: Inferred from mutant phenotype
32375023 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
30354798 GOA
Biological Process GO Annotation Evidence References Source
involved in centriole assembly IDA
IDA: Inferred from direct assay
30354798 GOA
involved in mitotic spindle assembly IDA
IDA: Inferred from direct assay
30354798 GOA
Cellular Component GO Annotation Evidence References Source
located in centriolar satellite IDA
IDA: Inferred from direct assay
30354798 GOA
part of centriolar subdistal appendage IDA
IDA: Inferred from direct assay
31789463 GOA
located in centrosome IDA
IDA: Inferred from direct assay
21399614 GOA
located in ciliary basal body IDA
IDA: Inferred from direct assay
32375023 GOA
located in microtubule organizing center IDA
IDA: Inferred from direct assay
30354798 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCDC61 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CCDC61 Q9Y6R9 CEP170 Homo sapiens Q5SW79
TAP
31789463
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11118A Biotinylated CCDC61 peptide TFA 99.90% Unkown
HY-P11118 Biotinylated CCDC61 peptide / Unkown