Search Result
Results for "
740
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-P0175
-
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740YPDGFR; PDGFR 740Y-P
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PI3K
Autophagy
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Cancer
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740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .
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- HY-126247
-
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Ras
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Cancer
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BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) by structure-based agent design with nanomolar affinity. BI-2852 is mechanistically distinct from covalent KRASG12C inhibitor (binds to switch II pocket) and binds ten-fold more strongly to active KRASG12D versus KRASwt (740 nM vs 7.5 μM). BI-2852 blocks GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.
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-
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- HY-19676
-
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VX-740; HMR 3480
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Caspase
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Inflammation/Immunology
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Pralnacasan (VX-740) is a potent, selective, non-peptide and orally active interleukin-1β converting enzyme (ICE, caspase 1) inhibitor with a Ki of 1.4 nM. Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment .
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- HY-118069
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-
-
- HY-135841
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CM010
1 Publications Verification
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Aldehyde Dehydrogenase (ALDH)
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Metabolic Disease
Cancer
|
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CM010 is a potent and selective aldehyde dehydrogenase 1A (ALDH1A) family inhibitor, with IC50s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM010 does not inhibit any of the other ALDH family members. CM010 can regulate metabolism and has anti-cancer activity .
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- HY-112624F
-
|
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Fluorescent Dye
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Others
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CY7-Dextran (MW 4000) is a fluorescent dye that consists of CY7 (HY-D0825) and Dextran (HY-112624) (Ex=740 nm; Em=770 nm). CY7-Dextran (MW 4000) can be used as a cell volume indicator and delineates the thin peripheral edges of the cells .
|
-
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- HY-114209
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MRK-740
2 Publications Verification
|
Histone Methyltransferase
|
Cancer
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MRK-740, a chemical probe, is a potent, selective and substrate-competitive PRDM9 histone methyltransferase inhibitor with an IC50 of 80?nM. MRK-740 is more selective for PRDM9 than other histone methyltransferases and other non-epigenetic targets. MRK-740 reduces PRDM9-dependent trimethylation of H3K4 (IC50?=?0.8?μM) .
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- HY-D2062
-
|
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Fluorescent Dye
Integrin
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Cancer
|
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ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .
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- HY-103416
-
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Dopamine Receptor
|
Neurological Disease
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A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor .
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- HY-D2873
-
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Sulfo Cy7(Et) tyramide
|
Fluorescent Dye
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Others
|
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Sulfo Cy7 tyramide, a red fluorescent dye (Ex=740 nm, Em=770 nm), is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). Sulfo Cy7 tyramide can be used for multiplex Immunohistochemistry (mIHC) .
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- HY-110089
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P2Y Receptor
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Inflammation/Immunology
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mrs 4062 (TEA) is a selective P2Y4 receptor agonist with an EC50 of 23 nM. mrs 4062 (TEA) has EC50s of 640 nM and 740 nM for P2Y2 and P2Y6, respectively .
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- HY-D2060
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Fluorescent Dye
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Others
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ATTO 740 is a near-infrared dye (Ex/Em: 740/764 nm). ATTO 740 can be conjugated with the Cetuximab antibody (HY-P9905) .
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- HY-126247B
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Drug Derivative
Ras
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Cancer
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(R)-BI-2852 is the isomer of BI-2852 (HY-126247), and can be used as an experimental control. BI-2852 is a KRAS inhibitor for the switch I/II pocket (SI/II-pocket) by structure-based agent design with nanomolar affinity. BI-2852 is mechanistically distinct from covalent KRASG12C inhibitor (binds to switch II pocket) and binds ten-fold more strongly to active KRASG12D versus KRASwt (740 nM vs 7.5 μM). BI-2852 blocks GEF, GAP, and effector interactions with KRAS, leading to inhibition of downstream signaling and an antiproliferative effect in KRAS mutant cells.
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- HY-79572
-
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Parasite
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Infection
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4-Methyl-3-nitrophenol is a phenolic compound classified as a soft electrophile. 4-Methyl-3-nitrophenol is toxic to ciliates, with a log IC50 value of -3.740 against T. pyriformis .
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- HY-176820
-
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Histone Methyltransferase
|
Cancer
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MRK-740-NC is a PRDM7/9 histone methyltransferase inhibitor. MRK-740-NC is a negative control compound of MRK-740 (HY-114209). MRK-740-NC has no inhibitory activity for PRDM7 and PRDM9 by replacing the methyl pyridine moiety of MRK-740 by a phenyl group .
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- HY-124086
-
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5-HT Receptor
|
Neurological Disease
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BHQ-O-5HT is a light-activated caged 5-HT protected by a BHQ group. When exposed to light at 365 or 740 nm, BHQ-O-5HT releases 5-HT through 1 or 2 photon excitation, respectively. BHQ-O-5HT can be manipulated in space and time to explore the role of 5-HT in regulating mood, appetite, memory, learning, and other cognitive functions .
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-
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- HY-P0175A
-
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740YPDGFR TFA; PDGFR 740Y-P TFA
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PI3K
Autophagy
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Cancer
|
|
740 Y-P TFA is a potent and cell-permeable PI3K activator. 740 Y-P TFA readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .
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- HY-D2676
-
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Fluorescent Dye
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Others
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Cy7 HA (MW 3000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-150970
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Pyroptosis
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Cancer
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ICy-OH, an iodinated photosensitizer, is an effective anticancer agent. ICy-OH can be used not only for deep tissue imaging (λex=640 nm,λem=690-740 nm) but also to selectively induce cell death in pancreatic cancer cells via cell pyroptosis pathway .
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- HY-141496
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Dopamine Receptor
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Neurological Disease
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A-77636 is an orally active, potent, selective and long-acting dopamine D1 receptor agonist (pEC50 = 8.13; EC50 = 1.1 nM). A-77636 shows the highest affinity (pKi = 7.40 ± 0.09; Ki = 39.8 nM) for the dopamine D1 receptor. A-77636 shows antiparkinsonian activity .
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- HY-D2061
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Fluorescent Dye
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Others
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ATTO 740 carboxy is a carboxyl derivative of ATTO 740, the maximum excitation/emission wavelength is: 743/763 nm.
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- HY-D2076
-
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Fluorescent Dye
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Others
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ATTO 740 biotin is a biotin derivative of ATTO 740 with maximum excitation/emission wavelengths: 743/763 nm.
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- HY-18332B
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Dopamine Transporter
Adrenergic Receptor
5-HT Receptor
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Neurological Disease
|
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DOV-102,677 is an orally sctive triple monoamine neurotransmitter reuptake inhibitor that simultaneously inhibits the dopamine (DAT) (IC50 = 129 nM; Ki = 222 nM), norepinephrine (NET) (IC50 = 103 nM; Ki = 1030 nM), and serotonin (SERT) (IC50 = 133 nM; Ki = 740 nM) transporters. DOV-102,677 demonstrated significant antidepressant-like activity and sensory-motor gating regulatory effects in mouse experiments. DOV-102,677 can be used for research on depression .
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- HY-D2075
-
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Fluorescent Dye
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Others
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ATTO 740 streptavidin is a streptavidin derivative of ATTO 740, it can label protein or antibody, the maximum excitation/emission wavelength: 743/763 nm.
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- HY-D2063
-
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Fluorescent Dye
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Others
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ATTO 740 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 maleimide is a maleimide derivative of ATTO 740, which can be used to label proteins or antibodies.
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- HY-W953385
-
|
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Ligands for E3 Ligase
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Cancer
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CRBN ligand-740 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-740 can be linked to a target protein ligand via a linker to form a PROTAC.
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- HY-RS16171
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Small Interfering RNA (siRNA)
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Others
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ZNF740 Human Pre-designed siRNA Set A contains three designed siRNAs for ZNF740 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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ZNF740 Human Pre-designed siRNA Set A
ZNF740 Human Pre-designed siRNA Set A
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- HY-P2515
-
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Histone Acetyltransferase
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Others
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Transcriptional Intermediary Factor 2 (TIF2) (740-753) is a TIF-2 coactivator peptide composed of 14 amino acids and covers the residue range 740-753 of TIF-2 protein .
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- HY-100570
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-
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- HY-D2677
-
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Fluorescent Dye
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Others
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Cy7 HA (MW 100000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2675
-
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Fluorescent Dye
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Others
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Cy7 HA (MW 10000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2674
-
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Fluorescent Dye
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Others
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Cy7 HA (MW 7000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2672
-
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Fluorescent Dye
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Others
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Cy7 HA (MW 3000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2687
-
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Fluorescent Dye
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Others
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Cy7 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
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- HY-D2688
-
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Fluorescent Dye
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Others
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Cy7 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
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- HY-D2852
-
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Fluorescent Dye
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Others
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Heparin-Cy7 is a fluorescent dye composed of CY7 (HY-D0825) and heparin. Heparin-CY7 is used to study the localization and distribution of heparin in vivo and its interaction with other biomolecules (Ex/Em = 740/770 nm).
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- HY-D2685
-
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Fluorescent Dye
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Others
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Cy7 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D2681
-
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Fluorescent Dye
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Others
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Cy7 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D2683
-
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Fluorescent Dye
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Others
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Cy7 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D2684
-
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Fluorescent Dye
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Others
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Cy7 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-162045
-
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Biochemical Assay Reagents
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Cancer
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Ru-4T is a phototherapy agent. Ru-4T has phototherapeutic efficacy (PI = 114,000) against melanoma cells (SK-MEL-28) under broad-band visible light (400-700 nm) with EC50 values of 740 pM .
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- HY-D3005
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Fluorescent Dye
Autophagy
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Inflammation/Immunology
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NpCy-4 is a reliable reporter for monitoring lysosomal pH and viscosity changes in real time during Autophagy (λex = 650 nm; λem = 660-740 nm). NpCy-4 demonstrates a superior signal-to-background ratio (SBR) for cellular imaging. NpCy-4 facilitates real-time, noninvasive diagnostic imaging of acute gastritis model with high contrast .
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- HY-136675
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Fluorescent Dye
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Others
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ASMI is a ratiometric, two-photon excited fluorescent probe, composed of a highly two-photon active and biocompatible merocyanine fluorophore and an acrylate moiety as a thiol reactive site. ASMI is able to selectively detect and monitor mitochondrial Cys with rapid responsiveness, imaging living cells and intact tissues with high contrast and brightness at a depth of 150 μm. The two-photon action cross section (Φσmax) of ASMI is 65.2 GM, corresponding to an excitation wavelength (λex) of 740 nm.
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- HY-172966
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EGFR
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Cancer
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EG31 is an EGFR inhibitor. EG31 effectively inhibits the proliferation of triple-negative breast cancer (TNBC) cells (GI50 values of MDA-MB-231 and Hs578T cells are 498.90 nM and 740.73 nM, respectively) and induces apoptosis by inhibiting the EGFR signaling pathway. EG31 still maintains antiproliferative activity against 5-fluorouracil (5-FU)-resistant TNBC cells (GI50: 519.5 nM). EG31 can be used to study TNBC resistance .
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-
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- HY-171448
-
-
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- HY-D3152
-
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Fluorescent Dye
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Others
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NRh-Cu is a highly sensitive near-infrared fluorescence turn-on indicator and Cu 2+-selective probe (λex=680 nm, λem=740 nm). When NRh-Cu interacts with Cu 2+, it undergoes a structural transition from a non-fluorescent spirocyclic state to a fluorescent ring-opened state, which drives the enhancement of fluorescence emission. NRh-Cu can be used for Cu 2+ imaging in live cells and in vivo .
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- HY-D2680
-
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Fluorescent Dye
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Others
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Cy7 HA (MW 200000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2678
-
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Fluorescent Dye
|
Others
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Cy7 HA (MW 500000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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-
-
- HY-D2673
-
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Fluorescent Dye
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Others
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Cy7 HA (MW 55000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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-
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- HY-D2686
-
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Fluorescent Dye
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Others
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Cy7 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
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- HY-137073
-
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Fluorescent Dye
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Others
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Cy7 alkyne chloride is a dye derivative of Cyanine 7 (Cy7) containing an alkyne functional group (Ex/Em = 740/770 nm). The alkyne functionality of Cy7 alkyne chloride can react with molecules containing the azide functionality to form covalent bonds .
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- HY-158112
-
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Herbicide
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Others
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Herbicidal agent 3 (compound 7A) shows herbicidal activity against Digitaria sanguinalis and Amaranthus retroflexus at a dosage of 90 g ai/ha. Herbicidal agent 3 inhibites Setaria viridis TKL (SvTKL) enzyme activity, with the IC50 of 0.740 mg/L .
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- HY-D2682
-
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Fluorescent Dye
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Others
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Cy7 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D3028
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HSA-CY7
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Fluorescent Dye
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Others
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Human Serum Albumin-CY7 (HSA-CY7) is a CY7 (HY-D0825) labeled serum albumin. Human Serum Albumin-CY7 plays an important role in fluorescent labeling, drug delivery research, and other fields (Ex/Em = 740/770 nm) .
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- HY-D3021
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Fluorescent Dye
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Others
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CY7-Alginate is a CY7 (HY-D0825)-labeled alginate. CY7-Alginate combines the polysaccharide properties of alginate with the fluorescence properties of CY7, playing an important role in fields such as fluorescent labeling, cell imaging, and drug delivery research (Ex/Em = 740/770 nm).
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- HY-181783
-
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Glycosidase
STAT
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Neurological Disease
Cancer
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CHI3L1-IN-7 is a selective CHI3L1 inhibitor with a Kd of 7.40 μM and an IC50 of 15.4 μM. CHI3L1-IN-7 blocks CHI3L1's interaction with galectin-3, inhibits STAT3 phosphorylation, reduces the viability of multicellular 3D glioblastoma spheroids. CHI3L1-IN-7 can be used for the research of glioblastoma and CHI3L1-mediated tumor immune regulation .
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- HY-D3311
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Fluorescent Dye
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Cancer
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M1219 is a GSH/ATP dual near-infrared activated fluorescent probe that enables independent real-time monitoring of dynamic changes in intracellular GSH and ATP without spectral crosstalk (GSH: Ex=640 nm, Em=740~800 nm; ATP: Ex=594 nm/610 nm, Em=650~700 nm). M1219 not only visualizes the metabolic regulatory mechanism of TNBC under single/dual-target inhibition of SLC7A11/GLUT1 and accurately evaluates its in vivo efficacy, but also achieves precise localization of the TNBC tumor invasion boundary. M1219 can be used for the research of triple-negative breast cancer .
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| Cat. No. |
Product Name |
Type |
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- HY-112624F
-
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Fluorescent Dye
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CY7-Dextran (MW 4000) is a fluorescent dye that consists of CY7 (HY-D0825) and Dextran (HY-112624) (Ex=740 nm; Em=770 nm). CY7-Dextran (MW 4000) can be used as a cell volume indicator and delineates the thin peripheral edges of the cells .
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- HY-D2062
-
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Fluorescent Dye
|
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ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .
|
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- HY-D2873
-
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Sulfo Cy7(Et) tyramide
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Fluorescent Dye
|
|
Sulfo Cy7 tyramide, a red fluorescent dye (Ex=740 nm, Em=770 nm), is utilized as reporter fluorescent substrate of horseradish peroxidase (HRP)-catalyzed deposition for tyramide signal amplification (TSA). Sulfo Cy7 tyramide can be used for multiplex Immunohistochemistry (mIHC) .
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- HY-D2060
-
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Fluorescent Dye
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ATTO 740 is a near-infrared dye (Ex/Em: 740/764 nm). ATTO 740 can be conjugated with the Cetuximab antibody (HY-P9905) .
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- HY-D2676
-
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Fluorescent Dye
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Cy7 HA (MW 3000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2061
-
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Fluorescent Dye
|
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ATTO 740 carboxy is a carboxyl derivative of ATTO 740, the maximum excitation/emission wavelength is: 743/763 nm.
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- HY-D2076
-
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Fluorescent Dye
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ATTO 740 biotin is a biotin derivative of ATTO 740 with maximum excitation/emission wavelengths: 743/763 nm.
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- HY-D2075
-
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Fluorescent Dye
|
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ATTO 740 streptavidin is a streptavidin derivative of ATTO 740, it can label protein or antibody, the maximum excitation/emission wavelength: 743/763 nm.
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- HY-D2063
-
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Fluorescent Dye
|
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ATTO 740 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 maleimide is a maleimide derivative of ATTO 740, which can be used to label proteins or antibodies.
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-
- HY-D2677
-
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Fluorescent Dye
|
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Cy7 HA (MW 100000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 100000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2675
-
|
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Fluorescent Dye
|
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Cy7 HA (MW 10000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 10000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2674
-
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Fluorescent Dye
|
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Cy7 HA (MW 7000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 7000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2672
-
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Fluorescent Dye
|
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Cy7 HA (MW 3000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 3000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
|
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- HY-D2687
-
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Fluorescent Dye
|
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Cy7 HA biotin 5000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 5000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
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- HY-D2688
-
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Fluorescent Dye
|
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Cy7 HA biotin 10000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 10000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
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- HY-D2852
-
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Fluorescent Dye
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Heparin-Cy7 is a fluorescent dye composed of CY7 (HY-D0825) and heparin. Heparin-CY7 is used to study the localization and distribution of heparin in vivo and its interaction with other biomolecules (Ex/Em = 740/770 nm).
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- HY-D2685
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Fluorescent Dye
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Cy7 HA MA (MW 100000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 100000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D2681
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Fluorescent Dye
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Cy7 HA MA (MW 3000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 3000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D2683
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Fluorescent Dye
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Cy7 HA MA (MW 10000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 10000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D2684
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Fluorescent Dye
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Cy7 HA MA (MW 50000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 50000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D3005
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Fluorescent Dye
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NpCy-4 is a reliable reporter for monitoring lysosomal pH and viscosity changes in real time during Autophagy (λex = 650 nm; λem = 660-740 nm). NpCy-4 demonstrates a superior signal-to-background ratio (SBR) for cellular imaging. NpCy-4 facilitates real-time, noninvasive diagnostic imaging of acute gastritis model with high contrast .
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- HY-D3152
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Fluorescent Dye
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NRh-Cu is a highly sensitive near-infrared fluorescence turn-on indicator and Cu 2+-selective probe (λex=680 nm, λem=740 nm). When NRh-Cu interacts with Cu 2+, it undergoes a structural transition from a non-fluorescent spirocyclic state to a fluorescent ring-opened state, which drives the enhancement of fluorescence emission. NRh-Cu can be used for Cu 2+ imaging in live cells and in vivo .
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- HY-D2680
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Fluorescent Dye
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Cy7 HA (MW 200000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 200000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2678
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Fluorescent Dye
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Cy7 HA (MW 500000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 500000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2673
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Fluorescent Dye
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Cy7 HA (MW 55000) is a hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA (MW 5000) is widely used for cell imaging and in vivo imaging of shallow tissue (Ex/Em = 740/770 nm).
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- HY-D2686
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Fluorescent Dye
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Cy7 HA biotin 3000 is a biotinylated hyaluronic acid labeled with CY7 (HY-D0825). Cy7 HA biotin 3000 is widely used for cell imaging and in vivo imaging of shallow tissues (Ex/Em = 740/770 nm).
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- HY-137073
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Fluorescent Dye
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Cy7 alkyne chloride is a dye derivative of Cyanine 7 (Cy7) containing an alkyne functional group (Ex/Em = 740/770 nm). The alkyne functionality of Cy7 alkyne chloride can react with molecules containing the azide functionality to form covalent bonds .
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- HY-D2682
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Fluorescent Dye
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Cy7 HA MA (MW 5000) is a hyaluronic acid methacrylate labeled with CY7 (HY-D0825). Cy7 HA MA (MW 5000) is widely used in the fields of biolabeling and imaging, drug delivery and tissue engineering and regenerative medicine (Ex/Em = 740/770 nm).
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- HY-D3028
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HSA-CY7
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Fluorescent Dye
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Human Serum Albumin-CY7 (HSA-CY7) is a CY7 (HY-D0825) labeled serum albumin. Human Serum Albumin-CY7 plays an important role in fluorescent labeling, drug delivery research, and other fields (Ex/Em = 740/770 nm) .
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- HY-D3021
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Fluorescent Dye
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CY7-Alginate is a CY7 (HY-D0825)-labeled alginate. CY7-Alginate combines the polysaccharide properties of alginate with the fluorescence properties of CY7, playing an important role in fields such as fluorescent labeling, cell imaging, and drug delivery research (Ex/Em = 740/770 nm).
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- HY-D3311
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Fluorescent Dye
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M1219 is a GSH/ATP dual near-infrared activated fluorescent probe that enables independent real-time monitoring of dynamic changes in intracellular GSH and ATP without spectral crosstalk (GSH: Ex=640 nm, Em=740~800 nm; ATP: Ex=594 nm/610 nm, Em=650~700 nm). M1219 not only visualizes the metabolic regulatory mechanism of TNBC under single/dual-target inhibition of SLC7A11/GLUT1 and accurately evaluates its in vivo efficacy, but also achieves precise localization of the TNBC tumor invasion boundary. M1219 can be used for the research of triple-negative breast cancer .
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| Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P0175
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740YPDGFR; PDGFR 740Y-P
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PI3K
Autophagy
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Cancer
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740 Y-P (740YPDGFR; PDGFR 740Y-P) is a potent and cell-permeable PI3K activator. 740 Y-P readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .
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- HY-P0175A
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740YPDGFR TFA; PDGFR 740Y-P TFA
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PI3K
Autophagy
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Cancer
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740 Y-P TFA is a potent and cell-permeable PI3K activator. 740 Y-P TFA readily binds GST fusion proteins containing both the N- and C- terminal SH2 domains of p85 but fails to bind GST alone .
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- HY-P2515
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Histone Acetyltransferase
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Others
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Transcriptional Intermediary Factor 2 (TIF2) (740-753) is a TIF-2 coactivator peptide composed of 14 amino acids and covers the residue range 740-753 of TIF-2 protein .
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| Cat. No. |
Product Name |
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Classification |
-
- HY-RS16171
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siRNAs
Human Pre-designed siRNA Sets
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ZNF740 Human Pre-designed siRNA Set A contains three designed siRNAs for ZNF740 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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