RPL19 - ribosomal protein L19 Gene

Also Known as L19

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6143

About RPL19

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:39,200,283-39,204,732 (from NCBI)

This gene has 13 transcripts (splice variants) and 240 orthologues. Ubiquitous expression in ovary (RPKM 933.9), lymph node (RPKM 615.1) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RPL19 Products (2)

mRNA Protein Name
NM_000981.4 NP_000972.1 60S ribosomal protein L19 isoform 1
NM_001330200.1 NP_001317129.1 60S ribosomal protein L19 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Referencias Source
enables protein binding IPI
IPI: Inferred from physical interaction
21044950 GOA
enables structural constituent of ribosome IDA
IDA: Inferred from direct assay
23636399 GOA
Biological Process GO Annotation Evidence Referencias Source
involved in cytoplasmic translation IDA
IDA: Inferred from direct assay
25957688 GOA
Cellular Component GO Annotation Evidence Referencias Source
part of cytosolic large ribosomal subunit IDA
IDA: Inferred from direct assay
25957688 GOA
part of cytosolic large ribosomal subunit IPI
IPI: Inferred from physical interaction
25901680 GOA
located in cytosolic ribosome IDA
IDA: Inferred from direct assay
23636399 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RPL19 Protein Structure

Ribosomal_L19e

Ribosomal_L19e: Ribosomal protein L19e (3 - 148)

  • 0
  • 100
  • 196 a.a.
Protein Preferred Names Protein Names

60S ribosomal protein L19

  • large ribosomal subunit protein eL19

RPL19 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Referencias
Intra
RPL19 P84098 MRPL49 Homo sapiens Q13405
Anti Tag CoIP
33961781
Intra
RPL19 P84098 TERF1 Homo sapiens P54274
BiFC
21044950
Intra
RPL19 P84098 TERF1 Homo sapiens P54274
Pull Down
21044950
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Psoriasis 13

  • PSORS13

  • Psoriasis 13, Susceptibility To

  • Psoriasis

  • Psoriasis Vulgaris

  • Psoriasis Susceptibility 13

  • Pv

  • Psoriasis, Susceptibility To, Type 13
Diamond-Blackfan Anemia

  • Congenital Pure Red Cell Aplasia

  • Aase Syndrome

  • Erythrogenesis Imperfecta

  • Anemia, Diamond-Blackfan

  • Congenital Hypoplastic Anemia

  • Aase-Smith Ii Syndrome

  • Bds

  • Blackfan-Diamond Anemia

  • Congenital Prca

  • Congenital Hypoplastic Anemia, Blackfan-Diamond Type

  • Dba

  • Blackfan - Diamond Syndrome

  • Chronic Constitutional Pure Red Cell Anaemia

  • Anemia Diamond Blackfan Type

  • Anemia Congenital Erythroid Hypoplastic

  • Aregenerative Anemia Chronic Congenital

  • Blackfan Diamond Syndrome

  • Red Cell Aplasia, Pure Hereditary

  • Aase-Smith Syndrome Ii

  • Bda

  • Blackfan Diamond Anemia

  • Blackfan-Diamond Disease

  • Blackfan-Diamond Syndrome

  • Chronic Congenital Agenerative Anemia

  • Congenital Erythroid Hypoplastic Anemia

  • Congenital Hypoplastic Anemia Of Blackfan And Diamond

  • Congenital Pure Red Cell Anemia

  • Hypoplastic Congenital Anemia

  • Inherited Erythroblastopenia

  • Pure Hereditary Red Cell Aplasia

  • Anemia, Hypoplastic, Congenital

  • Anemia Hypoplastic Congenital

  • Fanconi Anemia

  • Constitutional Aplastic Anemia

  • Diamond-Blackfan Anemia 1

  • Aase Smith Syndrome 2

  • Congenital Red Cell Aplasia

  • Red Cell Aplasia Of Infants

  • Pure Red Cell Aplasia Of Infants

  • Congenital Red Cell Aplastic Anaemia

  • Congenital Pure Red Cell Anaemia

  • Congenital Erythroid Hypoplasia

  • Pearson Marrow-Pancreas Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS12171 RPL19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RPL19 VGNC VGNC:45715
Bos taurus RPL19 VGNC VGNC:49956
Mus musculus RPL19 MGD MGI:98020
Felis catus RPL19 VGNC VGNC:99436
Rattus norvegicus RPL19 RGD RGD:621183
Others RPL19 NCBI