DCTPP1 - dCTP pyrophosphatase 1 Gene

Homo sapiens

Also known as CDA03; RS21C6; XTP3TPA

Gene ID: 79077 | Gene type: protein coding

About DCTPP1

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:30,423,615-30,430,030 (from NCBI)

This gene has 6 transcripts (splice variants) and 175 orthologues. Ubiquitous expression in colon (RPKM 23.2), lymph node (RPKM 13.8) and 25 other tissues.

Summary

The protein encoded by this gene is dCTP pyrophosphatase, which converts dCTP to dCMP and inorganic pyrophosphate. The encoded protein also displays weak activity against dTTP and dATP, but none against dGTP. This protein may be responsible for eliminating excess dCTP after DNA synthesis and may prevent overmethylation of CpG islands. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]

DCTPP1 Products(1)

mRNA	Protein	Name
NM_024096.2	NP_077001.1	dCTP pyrophosphatase 1

DCTPP1 Protein Structure

MazG

0
100
170 a.a.

Protein Preferred Names

Protein Names

dCTP pyrophosphatase 1

XTP3-transactivated gene A protein

Recombinant DCTPP1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77508	XTP3TPA Protein, Human (His)	Q9H773 (M1-T170)	≥95%

Related Diseases

Diseases

Alias

Buschke-Ollendorff Syndrome

BOS	Dermatoosteopoikilosis
Dermatofibrosis Lenticularis Disseminata With Osteopoikilosis	Osteopathia Condensans Disseminata
Dermatofibrosis Lenticularis Disseminata	Disseminated Dermatofibrosis With Osteopoikilosis
Dermatofibrosis, Disseminated, With Osteopoikilosis	Osteopoikilosis With Or Without Melorheostosis
Dermatofibrosis, Disseminated With Osteopoikilosis	Dermatofibrosis Disseminata Lenticularis
Isolated Osteopoikilosis	Osteopoikilosis, Isolated

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03597	DCTPP1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	DCTPP1	MGD	MGI:1913672
Macaca mulatta	DCTPP1	VGNC	VGNC:104692
Bos taurus	DCTPP1	VGNC	VGNC:27934
Rattus norvegicus	DCTPP1	RGD	RGD:620933
Felis catus	DCTPP1	VGNC	VGNC:80562
Others	DCTPP1	NCBI

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