2. Gene
  3. SLC25A23 - solute carrier family 25 member 23 Gene

SLC25A23 - solute carrier family 25 member 23 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as APC2; MCSC2; SCAMC3; SCaMC-3

Gene ID: 79085 | Gene type: protein coding

About SLC25A23

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:6,436,081-6,459,792 (from NCBI)

This gene has 13 transcripts (splice variants), 198 orthologues and 49 paralogues. Ubiquitous expression in brain (RPKM 40.2), thyroid (RPKM 28.7) and 23 other tissues.

Summary

Predicted to enable ATP transmembrane transporter activity. Involved in calcium import into the mitochondrion; positive regulation of mitochondrial calcium ion concentration; and regulation of cellular hyperosmotic salinity response. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

SLC25A23 Products(1)

mRNA Protein Name
NM_024103.3 NP_077008.2 calcium-binding mitochondrial carrier protein SCaMC-3

SLC25A23 Protein Structure

EF-hand_6

EF-hand_6: EF-hand domain (16 - 41)

EF-hand_7

EF-hand_7: EF-hand domain pair (83 - 139)

Mito_carr

Mito_carr: Mitochondrial carrier protein (185 - 271)

Mito_carr

Mito_carr: Mitochondrial carrier protein (277 - 364)

Mito_carr

Mito_carr: Mitochondrial carrier protein (375 - 463)

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  • 468 a.a.
Protein Preferred Names Protein Names

calcium-binding mitochondrial carrier protein SCaMC-3

mitochondrial ATP-Mg/Pi carrier protein 2

Related Diseases

Diseases Alias
Ichthyosis, Congenital, Autosomal Recessive 11

Autosomal Recessive Congenital Ichthyosis 11

Ichthyosis With Hypotrichosis, Autosomal Recessive

Arih

Ichthyosis And Follicular Atrophoderma With Hypotrichosis And Hypohidrosis

Autosomal Recessive Ichthyosis With Hypotrichosis

ARCI11

Ifah

Hypotrichosis-Congenital Ichthyosis Syndrome

Ichthyosis-Follicular Atrophoderma-Hypotrichosis Syndrome

Ichthyosis-Follicular Atrophoderma-Hypotrichosis-Hypohidrosis Syndrome

Ichthyosis-Hypotrichosis Syndrome

Ifah Syndrome

Ihs
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13104 SLC25A23 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus SLC25A23 RGD RGD:1588586
Macaca mulatta SLC25A23 VGNC VGNC:107116
Mus musculus SLC25A23 MGD MGI:1914222
Bos taurus SLC25A23 VGNC VGNC:55309
Felis catus SLC25A23 VGNC VGNC:80716
Canis familiaris SLC25A23 VGNC VGNC:106610