CPLANE2 - ciliogenesis and planar polarity effector complex subunit 2 Gene

Also Known as RSG1; C1orf89

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79363

Summary

Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in axoneme assembly; intracellular protein localization; and regulation of vesicle-mediated transport. Predicted to act upstream of or within several processes, including endocardial cushion fusion; regulation of smoothened signaling pathway; and smoothened signaling pathway. Located in centriole; ciliary basal body; and ciliary transition zone. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in thyroid (RPKM 2.8), ovary (RPKM 1.9) and 25 other tissues.

CPLANE2 Products (1)

mRNA Protein Name
NM_030907.4 NP_112169.2 ciliogenesis and planar polarity effector 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Cellular Component GO Annotation Evidence References Source
located in centriole IDA
IDA: Inferred from direct assay
29038301 GOA
located in ciliary basal body IDA
IDA: Inferred from direct assay
29038301 GOA
located in ciliary transition zone IDA
IDA: Inferred from direct assay
29038301 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CPLANE2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CPLANE2 Q9BU20 RND3 Homo sapiens P61587
Y2H Array
32296183
Intra
CPLANE2 Q9BU20 RND3 Homo sapiens P61587
Y2H Prey Pooling
32296183
Intra
CPLANE2 Q9BU20 IMPDH2 Homo sapiens P12268
Y2H Array
32296183
Intra
CPLANE2 Q9BU20 IMPDH2 Homo sapiens P12268
Validated Y2H
25416956
Intra
CPLANE2 Q9BU20 IMPDH2 Homo sapiens P12268
Y2H Prey Pooling
32296183
Intra
CPLANE2 Q9BU20 FUZ Homo sapiens Q9BT04
Y2H Pooling
16189514
Intra
CPLANE2 Q9BU20 FUZ Homo sapiens Q9BT04
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03096 CPLANE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown