ZNF239 - zinc finger protein 239 Gene

Also Known as MOK2; HOK-2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8187

Summary

MOK2 proteins are DNA- and RNA-binding proteins that are mainly associated with nuclear RNP components, including the nucleoli and extranucleolar structures (Arranz et al., 1997 [PubMed 9121460]).[supplied by OMIM, Mar 2008]
Broad expression in testis (RPKM 1.5), prostate (RPKM 1.2) and 22 other tissues.

ZNF239 Products (11)

mRNA Protein Name
NM_001099282.2 NP_001092752.1 zinc finger protein 239 isoform a
NM_001099283.2 NP_001092753.1 zinc finger protein 239 isoform a
NM_001099284.2 NP_001092754.1 zinc finger protein 239 isoform a
NM_001324347.2 NP_001311276.1 zinc finger protein 239 isoform a
NM_001324348.2 NP_001311277.1 zinc finger protein 239 isoform a
NM_001324349.2 NP_001311278.1 zinc finger protein 239 isoform a
NM_001324350.2 NP_001311279.1 zinc finger protein 239 isoform a
NM_001324351.2 NP_001311280.1 zinc finger protein 239 isoform a
NM_001324352.2 NP_001311281.1 zinc finger protein 239 isoform b
NM_001324353.2 NP_001311282.1 zinc finger protein 239 isoform c
NM_005674.3 NP_005665.2 zinc finger protein 239 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
11278819 GOA
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
11278819 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
11278819 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11278819 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF239 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF239 Q16600 MTUS2 Homo sapiens Q5JR59-3
Validated Y2H
32296183
Intra
ZNF239 Q16600 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
ZNF239 Q16600 KRTAP10-6 Homo sapiens P60371
Y2H Prey Pooling
32296183
Intra
ZNF239 Q16600 KRTAP10-6 Homo sapiens P60371
Y2H Array
32296183
Intra
ZNF239 Q16600 CARD10 Homo sapiens Q9BWT7
Validated Y2H
32296183
Intra
ZNF239 Q16600 CARD10 Homo sapiens Q9BWT7
Y2H Prey Pooling
32296183
Intra
ZNF239 Q16600 CARD10 Homo sapiens Q9BWT7
Y2H Array
32296183
Intra
ZNF239 Q16600 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
ZNF239 Q16600 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
ZNF239 Q16600 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra
ZNF239 Q16600 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
ZNF239 Q16600 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Intra
ZNF239 Q16600 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
ZNF239 Q16600 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
25416956
Intra
ZNF239 Q16600 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
ZNF239 Q16600 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
32296183
Intra
ZNF239 Q16600 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
ZNF239 Q16600 GRN Homo sapiens P28799
Y2H Array
32814053
Intra
ZNF239 Q16600 GRN Homo sapiens P28799
Validated Y2H
32814053
Intra
ZNF239 Q16600 GRN Homo sapiens P28799
Y2H Pooling
32814053
Intra
ZNF239 Q16600 WTAP Homo sapiens Q15007
Y2H Prey Pooling
32296183
Intra
ZNF239 Q16600 WTAP Homo sapiens Q15007
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS16111 ZNF219 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16113 ZNF236 Human Pre-designed siRNA Set A Pre-designed Set / Unkown