H2AC13 - H2A clustered histone 13 Gene

Also Known as H2A/c; H2AFC; HIST1H2AI

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8329

Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]

H2AC13 Products (1)

mRNA Protein Name
NM_003509.3 NP_003500.1 histone H2A type 1
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
17980597 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
15161933 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
16319397 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

H2AC13 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
H2AC11 P0C0S8 DNAJC2 Homo sapiens Q99543 21179169
Intra
H2AC11 P0C0S8 BRPF1 Homo sapiens P55201
ITC
25281266
Intra
H2AC11 P0C0S8 YWHAZ Homo sapiens P63104 15161933
Intra
H2AC11 P0C0S8 RNF2 Homo sapiens Q99496 21179169
Intra
H2AC11 P0C0S8 IL33 Homo sapiens O95760 18688256
Cross: Cross-species interaction Intra: Intraspecies interaction

H2AC13 Antibodies

Cat. No. 상품명 신청 Reactivity
HY-P86131 Histone H2A (Ubiquityl Lys119) Antibody (YA5823) WB, IHC-P, ICC/IF, IP, ELISA Human, Mouse, Rat
HY-P86519 Histone H2A Antibody (YA6211) WB, IHC-P, ICC/IF, IP, ELISA Human, Mouse, Rat