2. Gene
  3. Rps6kb1 - ribosomal protein S6 kinase B1 Gene

Rps6kb1 - ribosomal protein S6 kinase B1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as p70 S6K-alpha

Gene ID: 83840 | Gene type: protein coding

About Rps6kb1

Primary_assembly 10: 71,323,777-71,367,908 reverse strand.mRatBN7.2:CM026983.1

This gene has 3 transcripts (splice variants), 155 orthologues, 7 paralogues and is associated with 17 phenotypes. Biased expression in Muscle (RPKM 16.2), Thymus (RPKM 146.) and 9 other tissues.

Summary

Enables several functions, including ATP binding activity; PDZ domain binding activity; and protein Phosphatase 2A binding activity. Involved in several processes, including long-term memory; positive regulation of skeletal muscle tissue growth; and response to peptide hormone. Located in several cellular components, including cell surface; cytosol; and perinuclear region of cytoplasm. Is active in synapse. Biomarker of several diseases, including autosomal dominant polycystic kidney disease; hyperinsulinism; muscular atrophy; obesity; and primary biliary cholangitis. Orthologous to human RPS6KB1 (ribosomal protein S6 kinase B1). [provided by Alliance of Genome Resources, Apr 2022]

Rps6kb1 Products(1)

mRNA Protein Name
NM_031985.1 NP_114191.1 ribosomal protein S6 kinase beta-1

Rps6kb1 Protein Structure

STKc_p70S6K

STKc_p70S6K: cd05584 (93 - 415)

  • 0
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  • 525 a.a.
Protein Preferred Names Protein Names

ribosomal protein S6 kinase beta-1

70 kDa ribosomal protein S6 kinase 1

P70S6K

P70S6K1

S6 kinase

S6K

S6K-beta-1

S6K1

p70 S6 kinase alpha

p70 S6KA

p70 ribosomal S6 kinase alpha

p70(S6K)-alpha

p70-S6K 1

ribosomal protein S6 kinase I

ribosomal protein S6 kinase, 70kDa, polypeptide 1

ribosomal protein S6 kinase, polypeptide 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148062 RSS0680 98.03% Unkown
HY-RS12262 RPS6KB1 Human Pre-designed siRNA Set A / Unkown
HY-RS12263 Rps6kb1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS12264 Rps6kb1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rps6kb1 NCBI NCBI:6198