ADGRG7 - adhesion G protein-coupled receptor G7 Gene

Homo sapiens

Also known as GPR128

Gene ID: 84873 | Gene type: protein coding

About ADGRG7

Cytogenetic location: 3q12.2 Genomic coordinates (GRCh38): 3:100,609,601-100,695,479 (from NCBI)

This gene has 5 transcripts (splice variants), 193 orthologues and 42 paralogues. Biased expression in duodenum (RPKM 18.5), small intestine (RPKM 17.4) and 2 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ADGRG7 Products(2)

mRNA	Protein	Name
NM_001308362.1	NP_001295291.1	adhesion G-protein coupled receptor G7 isoform 2 precursor
NM_032787.3	NP_116176.2	adhesion G-protein coupled receptor G7 isoform 1 precursor

ADGRG7 Protein Structure

GPS

7tm_2

0
200
400
600
797 a.a.

Protein Preferred Names

Protein Names

adhesion G-protein coupled receptor G7

G-protein coupled receptor 128

Related Diseases

Diseases

Alias

Fibrogenesis Imperfecta Ossium

Baker'S Disease

Osteogenesis Imperfecta, Type Xvii

Osteogenesis Imperfecta Type 17	OI17
Osteogenesis Imperfecta Type Xvii	Osteogenesis Imperfecta 17

Osteogenesis Imperfecta, Type Iv

Osteogenesis Imperfecta Type 4	Osteogenesis Imperfecta Type Iv
OI4	Oi, Type Iv
Osteogenesis Imperfecta With Normal Sclerae	Oi Type Iv
Oi Type 4	Osteogenesis Imperfecta With Normal Sclera
Common Variable Oi With Normal Sclerae	Osteogenesis Imperfecta 4
Oi-Iv

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00360	ADGRG7 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ADGRG7	MGD	MGI:2441732
Canis familiaris	ADGRG7	VGNC	VGNC:37649
Bos taurus	ADGRG7	VGNC	VGNC:25670
Macaca mulatta	ADGRG7	VGNC	VGNC:69636
Rattus norvegicus	ADGRG7	RGD	RGD:1307217
Felis catus	ADGRG7	VGNC	VGNC:59637

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