TBRG1 - transforming growth factor beta regulator 1 Gene

Also Known as NIAM; TB-5

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84897

Summary

Involved in several processes, including DNA replication; protein localization to nucleoplasm; and protein stabilization. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in brain (RPKM 12.4), spleen (RPKM 9.3) and 25 other tissues.

TBRG1 Products (1)

mRNA Protein Name
NM_032811.3 NP_116200.2 transforming growth factor beta regulator 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17110379 GOA
Biological Process GO Annotation Evidence References Source
involved in DNA replication IMP
IMP: Inferred from mutant phenotype
17110379 GOA
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
17110379 GOA
involved in protein localization to nucleoplasm IDA
IDA: Inferred from direct assay
17110379 GOA
involved in protein stabilization IMP
IMP: Inferred from mutant phenotype
17110379 GOA
acts upstream of regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
17110379 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
17110379 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TBRG1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TBRG1 Q3YBR2 PMP22 Homo sapiens A0A6Q8PF08
Y2H Pooling
32814053
Intra
TBRG1 Q3YBR2 PMP22 Homo sapiens A0A6Q8PF08
Validated Y2H
32814053
Intra
TBRG1 Q3YBR2 PMP22 Homo sapiens A0A6Q8PF08
Y2H Array
32814053
Intra
TBRG1 Q3YBR2 ZMYND19 Homo sapiens Q96E35
Validated Y2H
32296183
Intra
TBRG1 Q3YBR2 ZMYND19 Homo sapiens Q96E35
Anti Tag CoIP
33961781
Intra
TBRG1 Q3YBR2 SMYD1 Homo sapiens Q8NB12
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14268 TBR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14269 TBRG4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14948 TPRG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown