PHYKPL - 5-phosphohydroxy-L-lysine phospho-lyase Gene
Also Known as PHLU; AGXT2L2
Species: Homo sapiens (human)
Gene Type: protein coding
Gene ID: 85007
Summary
This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
PHYKPL Products (1)
| mRNA | Protein | Name |
|---|---|---|
| XR_008487187.1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables identical protein binding |
IPI
IPI: Inferred from physical interaction
|
16189514 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21044950 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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| Protein Preferred Names | Protein Names | |
|---|---|---|
|
5-phosphohydroxy-L-lysine phospho-lyase |
|
PHYKPL Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
PHYKPL | Q8IUZ5 | VAC14 | Homo sapiens | Q08AM6 | 25416956 | |
|
Intra
|
PHYKPL | Q8IUZ5 | VAC14 | Homo sapiens | Q08AM6 | 29892012 | |
|
Intra
|
PHYKPL | Q8IUZ5 | LNX2 | Homo sapiens | Q8N448 | 29892012 | |
|
Intra
|
PHYKPL | Q8IUZ5 | LNX2 | Homo sapiens | Q8N448 | 31515488 | |
|
Intra
|
PHYKPL | Q8IUZ5 | USO1 | Homo sapiens | O60763 | 25416956 | |
|
Intra
|
PHYKPL | Q8IUZ5 | USO1 | Homo sapiens | O60763 | 25416956 | |
|
Intra
|
PHYKPL | Q8IUZ5 | PHYKPL | Homo sapiens | Q8IUZ5 | 16189514 | |
|
Intra
|
PHYKPL | Q8IUZ5 | PHYKPL | Homo sapiens | Q8IUZ5 | 31515488 | |
|
Intra
|
PHYKPL | Q8IUZ5 | PHYKPL | Homo sapiens | Q8IUZ5 | 32296183 | |
|
Intra
|
PHYKPL | Q8IUZ5 | PHYKPL | Homo sapiens | Q8IUZ5 | 32296183 | |
|
Intra
|
PHYKPL | Q8IUZ5 | PHYKPL | Homo sapiens | Q8IUZ5 | 25416956 | |
|
Intra
|
PHYKPL | Q8IUZ5 | POT1 | Homo sapiens | Q9NUX5 | 21044950 | |
|
Intra
|
PHYKPL | Q8IUZ5 | PHYKPL | Homo sapiens | Q8IUZ5 | 32296183 | |
|
Intra
|
PHYKPL | Q8IUZ5 | GIT1 | Homo sapiens | Q9Y2X7 | 33961781 |
Cross: Cross-species interaction
Intra: Intraspecies interaction