DGKZ - diacylglycerol kinase zeta Gene

Homo sapiens

Also known as DAGK5; DAGK6; DGK-ZETA; hDGKzeta

Gene ID: 8525 | Gene type: protein coding

About DGKZ

Cytogenetic location: 11p11.2 Genomic coordinates (GRCh38): 11:46,332,926-46,380,554 (from NCBI)

This gene has 24 transcripts (splice variants), 273 orthologues and 9 paralogues. Ubiquitous expression in brain (RPKM 24.7), bone marrow (RPKM 15.6) and 24 other tissues.

Summary

The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2010]

DGKZ Products(7)

mRNA	Protein	Name
NM_001105540.2	NP_001099010.1	diacylglycerol kinase zeta isoform 4
NM_001199266.2	NP_001186195.1	diacylglycerol kinase zeta isoform 5
NM_001199267.2	NP_001186196.1	diacylglycerol kinase zeta isoform 6
NM_001199268.2	NP_001186197.1	diacylglycerol kinase zeta isoform 7
NM_003646.4	NP_003637.2	diacylglycerol kinase zeta isoform 2
NM_201532.3	NP_963290.1	diacylglycerol kinase zeta isoform 1
NM_201533.3	NP_963291.2	diacylglycerol kinase zeta isoform 3

DGKZ Protein Structure

C1_1

DAGK_cat

DAGK_acc

Ank_5

0
200
400
600
800
1000
1117 a.a.

Protein Preferred Names

Protein Names

diacylglycerol kinase zeta

DAG kinase zeta

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03724	DGKZ Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	DGKZ	VGNC	VGNC:39924
Macaca mulatta	DGKZ	VGNC	VGNC:71789
Bos taurus	DGKZ	VGNC	VGNC:54417
Rattus norvegicus	DGKZ	RGD	RGD:70929
Mus musculus	DGKZ	MGD	MGI:1278339
Felis catus	DGKZ	VGNC	VGNC:61464