2. Gene
  3. ASMTL - acetylserotonin O-methyltransferase like Gene

ASMTL - acetylserotonin O-methyltransferase like Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as ASTML; ASMTLX; ASMTLY

Gene ID: 8623 | Gene type: protein coding

About ASMTL

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:1,403,139-1,453,756 (from NCBI)

This gene has 6 transcripts (splice variants), 168 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 11.8), prostate (RPKM 10.4) and 25 other tissues.

Summary

The protein encoded by this gene has an N-terminus that is similar to the multicopy associated filamentation (maf) protein of Bacillus subtilis and to orfE of Escherichia coli, while the C-terminus is similar to N-acetylserotonin O-methyltransferase. This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

ASMTL Products(3)

mRNA Protein Name
NM_001173473.2 NP_001166944.1 probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein isoform 2
NM_001173474.2 NP_001166945.1 probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein isoform 3
NM_004192.4 NP_004183.2 probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein isoform 1

ASMTL Protein Structure

Maf

Maf: Maf-like protein (14 - 211)

Methyltransf_2

Methyltransf_2: O-methyltransferase (352 - 594)

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  • 621 a.a.
Protein Preferred Names Protein Names

probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein

N-acetylserotonin O-methyltransferase-like protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01097 ASMTL Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ASMTL RGD RGD:1306877
Felis catus ASMTL VGNC VGNC:68357
Bos taurus ASMTL VGNC VGNC:26215