1. Gene
  2. CYTIP - cytohesin 1 interacting protein Gene

CYTIP - cytohesin 1 interacting protein Gene

Homo sapiens

Also known as HE; B3-1; CASP; CYBR; CYTHIP; PSCDBP

Gene ID: 9595 | Gene type: protein coding

About CYTIP

Cytogenetic location: 2q24.1 Genomic coordinates (GRCh38): 2:157,414,619-157,444,089 (from NCBI)

This gene has 8 transcripts (splice variants), 200 orthologues and 1 paralogue. Biased expression in lymph node (RPKM 28.7), bone marrow (RPKM 27.5) and 11 other tissues.

Summary

The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.[provided by RefSeq, Aug 2008]

CYTIP Products(1)

mRNA Protein Name
NM_004288.5 NP_004279.3 cytohesin-interacting protein

CYTIP Protein Structure

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (78 - 161)

  • 0
  • 100
  • 200
  • 300
  • 359 a.a.
Protein Preferred Names Protein Names

cytohesin-interacting protein

cbp HE

Orthologs Information

Species Symbol Source ID
Mus musculus CYTIP MGD MGI:2183535
Macaca mulatta CYTIP VGNC VGNC:71831
Canis familiaris CYTIP VGNC VGNC:50297
Bos taurus CYTIP VGNC VGNC:49051
Rattus norvegicus CYTIP RGD RGD:1307990
Felis catus CYTIP VGNC VGNC:69098