2. Gene
  3. MRPL19 - mitochondrial ribosomal protein L19 Gene

MRPL19 - mitochondrial ribosomal protein L19 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as RLX1; L19mt; MRPL15; RPML15; MRP-L15; MRP-L19

Gene ID: 9801 | Gene type: protein coding

About MRPL19

Cytogenetic location: 2p12 Genomic coordinates (GRCh38): 2:75,646,783-75,662,206 (from NCBI)

This gene has 7 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in thyroid (RPKM 7.4), kidney (RPKM 7.1) and 25 other tissues.

Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

MRPL19 Products(1)

mRNA Protein Name
NM_014763.4 NP_055578.2 39S ribosomal protein L19, mitochondrial

MRPL19 Protein Structure

Ribosomal_L19

Ribosomal_L19: Ribosomal protein L19 (102 - 192)

  • 0
  • 100
  • 200
  • 292 a.a.
Protein Preferred Names Protein Names

39S ribosomal protein L19, mitochondrial

39S ribosomal protein L15, mitochondrial

Related Diseases

Diseases Alias
Dyslexia
Reading Disorder

Specific Reading Disorder

Reading

Dyslexia

Developmental Reading Disorder
Specific Language Impairment

Language Impairment, Specific
Learning Disability

Learning Disabilities

Learning Disorders

Academic Skill Disorder

Learning Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08666 MRPL19 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MRPL19 MGD MGI:1926274
Rattus norvegicus MRPL19 RGD RGD:1587381
Bos taurus MRPL19 VGNC VGNC:31622
Canis familiaris MRPL19 VGNC VGNC:43383
Felis catus MRPL19 VGNC VGNC:63597
Macaca mulatta MRPL19 VGNC VGNC:74743