1. GPCR/G Protein Neuronal Signaling
  2. Dopamine Receptor
  3. Glovadalenum

Glovadalenum (Glovadalen) is an orally active, selective, blood-brain barrier permeable positive allosteric modulator of dopamine D1 receptor. Glovadalenum selectively enhances the efficacy of dopamine in activating dopamine D1 receptor. Glovadalenum can be used for the research of Parkinson's disease.

For research use only. We do not sell to patients.

Glovadalenum

Glovadalenum Chemical Structure

CAS No. : 2576359-31-2

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Description

Glovadalenum (Glovadalen) is an orally active, selective, blood-brain barrier permeable positive allosteric modulator of dopamine D1 receptor. Glovadalenum selectively enhances the efficacy of dopamine in activating dopamine D1 receptor. Glovadalenum can be used for the research of Parkinson's disease[1].

IC50 & Target

D1 receptor[1]

In Vitro

Glovadalenum enhances the efficacy of dopamine in activating dopamine D1 receptors[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

476.40

Formula

C24H27Cl2N3O3

CAS No.
SMILES

O=C(N1[C@H](CC2=C(C(C)(O)C)C=CC=C2[C@@H]1C)CO)CC3=C4C(N(N=C4Cl)C)=CC=C3Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Glovadalenum
Cat. No.:
HY-159527
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