Glycyllysine
Based on 1 Customer Validation
Glycyllysine is a polypeptide that can be used in the synthesis of antibodies and amino acid type gemini surfactants. Glycyllysine has potential applications in modifying plasmid/gemini/lipid (P/G/L) nanoparticles transport carriers.
For research use only. We do not sell to patients.
- Purity: 95.34%
- CAS No.: 997-62-6
- Formula: C8H17N3O3
- Molecular Weight:203.24
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDCK | EC50 |
0.75 mM
Compound: 33
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Activation of human PEPT1 expressed in MDCK cells
Activation of human PEPT1 expressed in MDCK cells
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[PMID: 16759105] |
| MDCK | IC50 |
1.25 mM
Compound: 33
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Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
|
[PMID: 16759105] |
Chemical Information
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CAS No. 997-62-6
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Appearance Solid
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Molecular Weight 203.24
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Formula C8H17N3O3
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Color White to off-white
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Sequence
H-Gly-Lys-OH
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Sequence Shortening
GK
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 50 mg/mL (246.01 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Uehara T, et al. Design, synthesis, and evaluation of [188Re]organorhenium-labeled antibody fragments with renal enzyme-cleavable linkage for low renal radioactivity levels. Bioconjug Chem. 2007 Jan-Feb;18(1):190-8. [Content Brief]
[2]. Singh J, et al. Amino acid-substituted gemini surfactant-based nanoparticles as safe and versatile gene delivery agents. Curr Drug Deliv. 2011 May;8(3):299-306. [Content Brief]
[3]. Al-Dulaymi MA, et al. Di-Peptide-Modified Gemini Surfactants as Gene Delivery Vectors: Exploring the Role of the Alkyl Tail in Their Physicochemical Behavior and Biological Activity. AAPS J. 2016 Sep;18(5):1168-1181. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.9203 mL | 24.6015 mL | 49.2029 mL | 123.0073 mL |
| 5 mM | 0.9841 mL | 4.9203 mL | 9.8406 mL | 24.6015 mL | |
| 10 mM | 0.4920 mL | 2.4601 mL | 4.9203 mL | 12.3007 mL | |
| 15 mM | 0.3280 mL | 1.6401 mL | 3.2802 mL | 8.2005 mL | |
| 20 mM | 0.2460 mL | 1.2301 mL | 2.4601 mL | 6.1504 mL | |
| 25 mM | 0.1968 mL | 0.9841 mL | 1.9681 mL | 4.9203 mL | |
| 30 mM | 0.1640 mL | 0.8200 mL | 1.6401 mL | 4.1002 mL | |
| 40 mM | 0.1230 mL | 0.6150 mL | 1.2301 mL | 3.0752 mL | |
| 50 mM | 0.0984 mL | 0.4920 mL | 0.9841 mL | 2.4601 mL | |
| 60 mM | 0.0820 mL | 0.4100 mL | 0.8200 mL | 2.0501 mL | |
| 80 mM | 0.0615 mL | 0.3075 mL | 0.6150 mL | 1.5376 mL | |
| 100 mM | 0.0492 mL | 0.2460 mL | 0.4920 mL | 1.2301 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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