GRL-07524

GRL-07524 (Compound 4e) is a potent inhibitor of HIV-1 protease (Ki = 0.22 nM). GRL-07524 contains oxaspirocyclic carbamates as the P2 ligands. GRL-07524 exhibits good antiviral activity with an EC50 = 210 nM. GRL-07524 binds to the HIV-1 PR active site in one of the four symmetry independent molecules along with key catalytic residues.

For research use only. We do not sell to patients.

  • Formula: C38H50N2O8S
  • Molecular Weight:694.88
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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