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Cat. No.: HY-19511A

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GSK2018682 hydrochloride

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

GSK2018682 hydrochloride is an agonist for S1P1 and S1P5 receptor with pEC₅₀s of 7.7 and 7.2, respectively, and has no agonist activity towards human S1P2, S1P3, or S1P4. GSK2018682 hydrochloride is used in the research of multiple sclerosis.

For research use only. We do not sell to patients.

CAS No.: 1034687-52-9
Formula: C₂₂H₂₂Cl₂N₄O₄
Molecular Weight:477.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

GSK2018682 hydrochloride Chemical Structure

CAS No.: 1034687-52-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All LPL Receptor Isoforms :

Chemical Information

CAS No. 1034687-52-9
Molecular Weight 477.34
Formula C₂₂H₂₂Cl₂N₄O₄
SMILES

O=C(CCCN1C=CC2=C(C3=NOC(C4=CC(Cl)=C(OC(C)C)N=C4)=N3)C=CC=C21)O.Cl
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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ACS Infect Dis

Repurposing GSK2018682 Confers Dual Antibacterial and Antibiofilm Activity against Staphylococcus aureus. [Abstract]

2026 Feb 13;12(2):623-636. PMID: 41525229

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xu J, et al. Safety, pharmacokinetics, pharmacodynamics, and bioavailability of GSK2018682, a sphingosine-1-phosphate receptor modulator, in healthy volunteers. Clin Pharmacol Drug Dev. 2014 May;3(3):170-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

GSK2018682 hydrochloride

1 Cited Publications

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Publications (1)
Purity & Documentation
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GSK2018682 hydrochloride

Publications Citing Use of MedChemExpress (MCE) GSK2018682 hydrochloride

All LPL Receptor Isoforms

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

Calculators

Help & FAQs

GSK2018682 hydrochloride Related Classifications

HY-19511A Related Classifications