GSK2226649A
GSK2226649A (compound 2) is a novel activator of satellite cell proliferation and enhanced repair of damaged muscle.
For research use only. We do not sell to patients.
- CAS No.: 1848232-20-1
- Formula: C15H12ClFN6OS
- Molecular Weight:378.81
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
GSK2226649A (compound 2) (0.1-10μM) can dose-dependently promote the proliferation of muscle stem cells, and can effectively accelerate the repair of damaged skeletal muscle in an in vivo mouse model of skeletal muscle injury[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| Dose(mg) | route | Cmax(ng/mL) | Tmax(hrs) | T1/2(hrs) | AUC0-inf(h*ng/mL) |
| 30 | oral | 1384 | 0.5 | 1.6 | 1720 |
| 30 | SC | 1783 | 1.0 | 6.1 | 12077 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1848232-20-1
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Molecular Weight 378.81
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Formula C15H12ClFN6OS
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SMILES
O=C(N)C1=C(F)C=CC=C1NC2=NC(NCC3=NC=CS3)=NC=C2Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)