Halofuginone hydrochloride (Standard)
Halofuginone hydrochloride (Standard) (RU-19110 hydrochloride (Standard)) is the analytical standard of Halofuginone hydrochloride (HY-N1584B). This product is intended for research and analytical applications. Halofuginone hydrochloride (RU-19110 hydrochloride), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM. Halofuginone hydrochloride is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Halofuginone hydrochloride is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone hydrochloride has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects.
For research use only. We do not sell to patients.
- CAS No.: 1217623-74-9
- Formula: C16H18BrCl2N3O3
- Molecular Weight:451.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1217623-74-9
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Molecular Weight 451.14
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Formula C16H18BrCl2N3O3
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SMILES
O=C1C2=CC(Cl)=C(Br)C=C2N=CN1CC(C[C@H]3[C@@H](CCCN3)O)=O.Cl
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Synonyms
RU-19110 hydrochloride (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Halofuginone hydrochloride (Standard) Related Classifications
HY-N1584BR Related Classifications
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Keywords
- Halofuginone hydrochloride (Standard)
- 1217623-74-9
- RU-19110 hydrochloride (Standard)
- Reference Standards
- Calcium Channel
- DNA/RNA Synthesis
- Parasite
- Sodium Channel
- TGF-beta/Smad
- Ca2+ channels
- Ca channels
- Na channels
- Na+ channels
- Transforming growth factor beta
- type-I
- collagen
- collagen-1
- prolyl-tRNA
- osteoarthritis
- TGF-β
- Inhibitor
- inhibitor
- inhibit